Results 81 to 90 of about 4,093,256 (305)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
ES Materials and ManufacturingZinc aluminate (ZnAl2O4) nanoparticles, doped with strontium (Sr), were synthesized using the microwave combustion process, incorporating varying strontium levels (x = 0, 0.1, 0.3, and 0.5).
Sofia Nirmala Tharsiuse +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Enhancing delay fault coverage through low power segmented scan
, 2006 Reducing power dissipation during test has been an active area of academic and industrial research for the last few years and numerous low power DFT techniques and test generation procedures have been proposed. Segmented scan [17-20] has been shown to be
Reddy, Sudhakar M. +12 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
APLICACIÓN DE LA TÉCNICA Z-SCAN A MEDIOS SATURABLES
, 2002 "La técnica Z-scan (o técnica de barrido en z, como también se le llama) es una prueba óptica relativamente nueva, inventada en el año 1989; ésta técnica se aplica a materiales no lineales para medir la parte no lineal del índice de refracción y el ...
María del Rayo Aparicio
core
Considerations about Z-scan sensitivity improvement: theory versus experiments
, 2009 This paper reports an experimental demonstration of the improvement of the Z-scan technique’s sensitivity. It is shown that this sensitivity can be multiplied by a factor equal to almost 400 with the help of simple binary diffractive elements.
Cagniot, E. +11 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Influence of the photoinduced focal length of a thin nonlinear material in the Z-scan technique [PDF]
, 2007 In this paper the response purely refractive of a thin nonlinear material, in the z-scan technique experiment, is modeled as a lens with a focal length that is a function of some integer power of the incident beam radius.
CARLOS GERARDO TREVIÑO PALACIOS +4 more
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