Results 71 to 80 of about 4,093,256 (305)
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Using Image Analysis to Determine Ideal Aperture Conditions for Optimal Z-Scan Signal Quality
An image analysis technique that is insensitive to power fluctuations and beam steering issues, and can be used with non TEM00 Gaussian beams, is introduced to determine the nonlinear properties of materials using the well-known Z-scan experimental ...
Esa A. Jaatinen +7 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Schematic illustration of z-scan for E. coli experiments.
(A) Approximation of E. coli geometry by a cylinder with radius R. The scan axis z passes through the geometric center of the cylinder. (B) Z-scan fluorescence intensity profile of cylinder is modeled by Eq 18.
Kwang-Ho Hur (562936) +1 more
core +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Z-scan experiment on soluble carbon nanotubes
The Z-scan experiments were carried out to investigate the soluble carbon nanotubes. The thickness of sample is changed in order to study “thin” and “thick” sample respectively. The experiments are carried out using 8ns, 10Hz repetition rate laser pulses at 1064nm and 532nm.
null Zhang Peng +3 more
openaire +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Nonlinear Refraction of Gold Nanoparticles Suspended in Water [PDF]
This paper presents the results of the experimental investigations of the surface plasmon resonances and nonlinear refraction of water suspensions of gold nanoparticles coated with a polymer shell.
R.V. Gamernyk +5 more
doaj
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

