Results 121 to 130 of about 419,255 (408)

Comparative Analysis Of Zebrafish And Planarian Model Systems For Developmental Neurotoxicity Screens Using An 87-Compound Library [PDF]

open access: yes, 2019
There is a clear need to establish and validate new methodologies to more quickly and efficiently screen chemicals for potential toxic effects, particularly on development. The emergence of alternative animal systems for rapid toxicology screens presents
Collins, Eva-Maria S.   +4 more
core   +1 more source

Optical mapping of neuronal activity during seizures in zebrafish [PDF]

open access: yes, 2017
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a better understanding of the mechanisms underlying this pathology and improve our approaches to the development of new drugs.
Fornetto, C   +10 more
core   +3 more sources

Red Multi‐Resonant Thermally Activated Delayed Fluorescence Emitters as Bioimaging Agents

open access: yesAdvanced Optical Materials, EarlyView.
Multi‐resonant thermally activated delayed fluorescence (MR‐TADF) emitters have attracted strong interest for use in electroluminescent devices due to their high photoluminescence quantum yield and narrowband emission. These properties, along with red emission, are also crucial for bioimaging probes.
Changfeng Si   +4 more
wiley   +1 more source

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration

open access: yesNature Communications, 2018
Spinal cord injury leads to a massive response of innate immune cells in non-regenerating mammals, but also in successfully regenerating zebrafish. However, the role of the immune response in successful regeneration is poorly defined.
Themistoklis M. Tsarouchas   +13 more
semanticscholar   +1 more source

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

open access: yesAdvanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He   +16 more
wiley   +1 more source

Computational analysis of congenital heart disease associated SNPs: unveiling their impact on the gene regulatory system

open access: yesBMC Genomics
Congenital heart disease (CHD) is a prevalent condition characterized by defective heart development, causing premature death and stillbirths among infants.
Shikha Vashisht   +2 more
doaj   +1 more source

Polarization effects on fluorescence emission of zebrafish neurons using light-sheet microscopy [PDF]

open access: yesarXiv, 2022
Light-sheet fluorescence microscopy (LSFM) makes use of a thin plane of light to optically section and image transparent tissues or organisms {\it{in vivo}}, which has the advantages of fast imaging speed and low phototoxicity. In this paper, we have employed light-sheet microscopy to investigate the polarization effects on fluorescence emission of ...
arxiv  

Making Waves: New Developments in Toxicology With the Zebrafish.

open access: yesToxicological Sciences, 2018
The laboratory zebrafish (Danio rerio) is now an accepted model in toxicologic research. The zebrafish model fills a niche between in vitro models and mammalian biomedical models.
Katharine A. Horzmann, J. Freeman
semanticscholar   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

open access: yesAdvanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He   +11 more
wiley   +1 more source

Topological data analysis of zebrafish patterns [PDF]

open access: yes, 2019
Self-organized pattern behavior is ubiquitous throughout nature, from fish schooling to collective cell dynamics during organism development. Qualitatively these patterns display impressive consistency, yet variability inevitably exists within pattern-forming systems on both microscopic and macroscopic scales.
arxiv   +1 more source

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