Results 151 to 160 of about 373,753 (331)

Insights into organelle forming RNAs: Diversity, functions and future perspectives

Animal Models and Experimental Medicine, EarlyView.
RNA molecules play crucial roles in the formation and maintenance of cellular structures and organelles. These ‘organelle formation RNAs’ include ribosomal RNAs, paraspeckle‐forming RNAs, nuclear speckle‐forming RNAs, nucleolus‐forming RNAs, and cytoskeleton‐forming RNA.
Meng Gong, Xiangting Wang, Xiaolin Liang
wiley   +1 more source

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Effect of Freeze Drying and Hot Air Drying on the Composition and Bioactivities of Lipids from Razor Clam Sinonovacula constricta

Foods
Razor clams, which are rich in diverse lipids, are notable for their unique health benefits and functional properties. This study comprehensively characterized and compared the composition and bioactivities of razor clam lipids after freeze drying (FD ...
Dexu Wang, Runjia Chang, Changyu Liu, Jiaxun Li, Jibin Liu, Ning Li, Yun Zhang, Xiaobin Li, Peihai Li, Kechun Liu   +9 more
doaj   +1 more source

Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes

, 2005
Albrecht Kramer-Zucker, Stephanie Wiessner, Abbie M. Jensen, Iain A. Drummond   +3 more
openalex   +1 more source

Establishment of a biosafe murine model of skeletal tuberculosis using Mycobacterium smegmatis

Animal Models and Experimental Medicine, EarlyView.
This study developed a biosafe, accessible, and versatile murine model of bone TB using Mycobacterium smegmatis, a fast‐growing, nonpathogenic mycobacterial species with high genomic homology to Mycobacterium tuberculosis. Three infection routes—subperiosteal calvarial injection, intratibial injection, and intracardiac (left ventricular) inoculation ...
Yewei Jia, Yuhuai Guo, Yusheng Yang, Jie Zhang, Ziyang Zhang, Ying Qu, Jiulin Tan, Jie Shen, Nathachit Limjunyawong, Jianzhong Xu, Zehua Zhang, Fei Luo, Ce Dou   +12 more
wiley   +1 more source

Lethal toxicity of metformin on zebrafish during early embryonic development by multi-omics analysis

Scientific Reports
Metformin is an antidiabetic drug used in type 2 diabetes as well as indicators in polycystic ovary syndrome (PCOS) and cancer. Due to their increase in popularity, high amounts of metformin are being released into aquatic environments.
Ziyuan Lin, Mingfeng Liu, Feng Chen, Chanjuan Zhao, Yanyan Liu, Huaqin Sun   +5 more
doaj   +1 more source

Zebrafish nephrogenesis involves dynamic spatiotemporal expression changes in renal progenitors and essential signals from retinoic acid and irx3b

, 2011
Rebecca A. Wingert, Alan J. Davidson
openalex   +2 more sources

Malaysia's commemorative activities for the second Asia Laboratory Animal Day (ALAD)

Animal Models and Experimental Medicine, EarlyView.
Summary of Malaysia's ALAD 2025 initiatives, activities, institutional collaboration, and outcomes in strengthening ethical laboratory animal research and technical competency. Abstract Malaysia's commemoration of the second Asia Laboratory Animal Day (ALAD) in 2025 marked a notable step forward in strengthening national and regional laboratory animal ...
John Shia Kwong Siew
wiley   +1 more source

Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome

, 2018
Camilla Teng, Man-Chun Ting, D’Juan T. Farmer, Mia Brockop, Robert E. Maxson, J. Gage Crump   +5 more
openalex   +1 more source

Investigating the Role of FGF8 Signaling in Neurogenesis of the Developing Zebrafish Eye [PDF]

, 2015
In the embryonic zebrafish, the fibroblast growth factor 8a (FGF8) signaling network is essential for proper development and maintenance of retinal ganglion cells (RGCs) as well as the hyaloid vasculature, the vessels that supply the eye with nutrients ...
Flinn, Benjamin A
core   +1 more source