Results 161 to 170 of about 209,207 (313)

Animal models in molecular biology research: Challenges, ethical imperatives, and the path to human‐relevant translation

Animal Models and Experimental Medicine, EarlyView.
The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi, Md. Taslim Sarker, Ferdous‐Ul‐Haque Joy, Shahriar Mohd Shams, Tahmina Foyez, Md. Abdul Mazid, Syed Masudur Rahman Dewan   +6 more
wiley   +1 more source

Analysis of genes controlling notochord development in zebrafish.

, 2006
The notochord is a vital and defining organ in vertebrates. Mutagenesis screening in zebrafish identified seven 'dwarf mutants that lack notochord development grumpy, sleepy, bashful, dopey, happy, sneezy and doc.
Thomas, K.A.
core  

Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems

Advanced NanoBiomed Research, EarlyView.
Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai, Ayushi Priyam, Ahmed Rashed, Gebreselassie Addisu Tilaye, Kamal Poudel, Aaron G. Schultz, Richard J. Williams   +6 more
wiley   +1 more source

Divergent Roles of Zebrafish IGF1 Receptor a and b in Glucose and Lipid Metabolism. [PDF]

Int J Mol Sci
Bao J, Chen X, Zhai G, Jin X, He J, Yin Z, Lou Q.   +6 more
europepmc   +1 more source

Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges

Angewandte Chemie International Edition, EarlyView.
Controlling biological systems with small‐molecule chromophores has evolved into a powerful strategy and is applied from chemical biology to medicine. However, the complexity of in vivo systems cannot be matched by a single wavelength of light. Developing methods to combine and individually control multiple chromophores is crucial.
Nadja A. Simeth
wiley   +1 more source

Characterization of Agrin Function in Chicken and Zebrafish Embryogenesis.

, 2005
Agrin is an extracellular matrix heparan sulfate proteoglycan that plays a key role in the development of the neuromuscular junction (NMJ) by inducing the clustering of acetylcholine receptors at synaptic sites of the NMJ.
Kim, Min Jung
core  

Spontaneous preferences for visual stimuli in zebrafish larvae (Danio rerio)

reservedNello zebrafish, Danio rerio, le larve, fin dalla nascita nonostante siano ancora poco sviluppate, devono nutrirsi e nascondersi dai predatori in modo autonomo.
MIO BERTOLO, GIULIA
core  

Importance of developmental stage and microenvironment control in Zebrafish larvae cardiovascular studies. [PDF]

PLoS One
Fiorino P, Rosa Cauduro LF, Konig DS, Rosa Cauduro LF, Santos CA, Kavai JA, Duarte ID, Américo ALV.   +7 more
europepmc   +1 more source

PEG Alternatives in Liposomal Nanocarriers: Physicochemical Characteristics and Sustainable Process Strategies

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley   +1 more source

RNA Polymerase III subunit Polr3a is required for craniofacial cartilage and bone development in zebrafish. [PDF]

PLoS Genet
Lubash BT, Gutierrez R, Hansen NA, Fink K, Hopkins CA, Sands LB, Nelson JC, Watt KEN.   +7 more
europepmc   +1 more source