Results 271 to 280 of about 419,255 (408)

Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish [PDF]

, 2017
Gao, Meng, Hu, Xuebin, Jiang, Tao, Li, Chang, Liu, Fei, Liu, Jing Yu, Liu, Mugen, Liu, Xiliang, Lu, Zhaojing, Shu, Xinhua, Soares, Dinesh C., Tang, Zhaohui, Weng, Jun, Xiao, Qing, Yang, Lifang, Yu, Shanshan   +15 more
core   +1 more source

Pharmacological Inhibition of β Myosin II Disrupts Sarcomere Assembly in Human iPSC‐Derived Cardiac Myocytes

Cytoskeleton, EarlyView.
ABSTRACT Sarcomeres are the fundamental contractile units of striated muscle. The functional roles of the cardiac‐specific myosin heavy chains, MYH6 (α myosin II) and MYH7 (β myosin II) during sarcomere assembly remain controversial. To address this, we utilized a selective MYH7 inhibitor, mavacamten, in combination with siRNA‐mediated knockdown of ...
James B. Hayes, Dylan T. Burnette
wiley   +1 more source

Retinoic acid‐induced cell death in the wound epidermis of regenerating zebrafish fins [PDF]

, 1995
Patrizia Ferretti, Jacqueline Géraudie
openalex   +1 more source

Neurological Outcomes of Joint Exposure to Polystyrene Micro/Nanospheres and Silver Nanoparticles in Zebrafish. [PDF]

Environ Health Perspect
Song J, Pu Q, Chen C, Liu X, Zhang X, Wang Z, Yan J, Wang X, Wang H, Qian Q.   +9 more
europepmc   +1 more source

In Vitro and In Vivo Photothermal and Photoacoustic Activities of Polymeric Nanoparticles Loaded with Nickel, Palladium, and Platinum‐Bis(dithiolene) Complexes

ChemMedChem, EarlyView.
Molecular metal‐bis(dithiolene) photothermal agents are efficiently incorporated into water‐dispersible nanoparticles (NPs) constituted by a biocompatible polymer derived from poly(malic acid). The photoacoustic activity of these NPs is evaluated, and their photothermal properties under near‐infrared irradiation are used for photothermal therapy of ...
Jean‐Baptiste Pluta, Lamiaa M. A. Ali, Romain Guechaichia, Victorien Massé, Thiviya Parthipan, Nathalie Bellec, Sandrine Cammas‐Marion, Francois Varray, Christophe Nguyen, Magali Gary‐Bobo, Franck Camerel   +10 more
wiley   +1 more source

Zebrafish MiR-430 Promotes Deadenylation and Clearance of Maternal mRNAs

Science, 2006
Antonio J. Giráldez, Yuichiro Mishima, J. Rihel, R. Grocock, Stijn van Dongen, Kunio Inoue, Anton J. Enright, A. Schier   +7 more
semanticscholar   +1 more source

Green tea epigallocatechin gallate attenuate metabolic dysfunction-associated steatotic liver disease by regulation of pyroptosis. [PDF]

Lipids Health Dis
Zhang J, Wang S, Zhang T, Zi M, Wang S, Zhang Q.   +5 more
europepmc   +1 more source

Novel 4,5‐Dihydrothiazole‐phenylpiperazine Derivatives: Synthesis, Docking Studies and Pharmacological Evaluation as Serotonergic Agents

ChemMedChem, Accepted Article.
We have described the synthesis of a new series of LCAPs (long‐chain arylpiperazine) as serotoninergic ligands (FG 1‐18). The combination of structural elements including heterocyclic nucleus, propyl chain and 4,5‐dihydrothiazol‐2‐ylphenylpiperazines, led to the preparation of different derivatives tested for their affinity toward 5‐HT1A, 5‐HT2A and 5 ...
Giorgia Andreozzi, Natalia Karkoszka, Rosa Sparaco, Angela Corvino, Beatrice Severino, Vincenzo Santagada, Elisa Magli, Ewa Gibuła-Tarłowska, Jolanta H. Kotlińska, Kinga Gawel, Raffaele Capasso, Anna Lesniak, Nataliia Semenko, Agnieszka A. Kaczor, Anna Bielenica, Grażyna Biała, Giuseppe Caliendo, Ewa Kędzierska, Ferdinando Fiorino   +18 more
wiley   +1 more source

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

Proceedings of the National Academy of Sciences of the United States of America, 2013
Li-En Jao, S. Wente, Wenbiao Chen
semanticscholar   +1 more source

Identification and Clinical Evaluation of Potential Biomarkers for Breast Cancer Resistance Protein (BCRP/ABCG2)

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical inhibition and genetic variation of the Breast Cancer Resistance Protein (BCRP/ABCG2) efflux transporter can significantly influence drug exposure, highlighting the need for reliable BCRP functional biomarkers. This study aimed to identify and evaluate biomarkers predictive of BCRP function in humans.
Andrew M. Riselli, Sook Wah Yee, Jia Yang, Claire M. Brett, Kelsey Trumbach, Xujia Zhou, Renmeng Liu, Xiaomin Liang, Yurong Lai, Runlan Huo, Yongjun Xue, Hong Shen, Lei Zhang, Xinning Yang, Qi Liu, Shiew‐Mei Huang, Kathleen M. Giacomini   +16 more
wiley   +1 more source