Results 61 to 70 of about 419,255 (408)
Shikonin Inhibits Fin Regeneration in Zebrafish Larvae
Cells, 2022 Shikonin is a naphthoquinone compound extracted from Chinese comfrey for treating cancer. However, there are few reports on its research on vertebrate tissue regeneration. Zebrafish is an ideal model for studying organ regeneration.
Zigang Cao +8 more
doaj +1 more source
Multilayer Perceptron Network Discriminates Larval Zebrafish Genotype using Behaviour [PDF]
arXiv, 2022 Zebrafish are a common model organism used to identify new disease therapeutics. High-throughput drug screens can be performed on larval zebrafish in multi-well plates by observing changes in behaviour following a treatment. Analysis of this behaviour can be difficult, however, due to the high dimensionality of the data obtained.
arxiv
In vivo imaging of embryonic vascular development using transgenic zebrafish.
Developmental Biology, 2002 In this study we describe a model system that allows continuous in vivo observation of the vertebrate embryonic vasculature. We find that the zebrafish fli1 promoter is able to drive expression of enhanced green fluorescent protein (EGFP) in all blood ...
N. Lawson, B. Weinstein
semanticscholar +1 more source
A Zebrafish Model of Mycobacterium leprae Granulomatous Infection. [PDF]
, 2017 Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in
Cameron, James +2 more
core +2 more sources
, 2016 The overall architecture and cell types are highly conserved from mammals to teleost fish. The rapid transparent ex utero development in zebrafish allows direct access and precise visualization of all the major events in cerebellar development. The superficial position of the cerebellar primoridum and cerebellum further facilitates in vivo imaging of ...
Kaslin, Jan, Brand, Michael
openaire +2 more sources
Live-imaging of astrocyte morphogenesis and function in zebrafish neural circuits
Nature Neuroscience, 2020 How astrocytes grow and integrate into neural circuits remains poorly defined. Zebrafish are well suited for such investigations, but bona fide astrocytes have not been described in this system.
Jiakun Chen +3 more
semanticscholar +1 more source
BE4max and AncBE4max Are Efficient in Germline Conversion of C:G to T:A Base Pairs in Zebrafish
Cells, 2020 The ease of use and robustness of genome editing by CRISPR/Cas9 has led to successful use of gene knockout zebrafish for disease modeling. However, it still remains a challenge to precisely edit the zebrafish genome to create single-nucleotide ...
Blake Carrington +2 more
doaj +1 more source
Pathogens, 2021 Intraocular inflammation following mycobacterial dissemination to the eye is common in tuberculosis (TB)-endemic countries. However, the early host–pathogen interactions during ocular dissemination are unknown.
Santhosh Kumar Damera +3 more
doaj +1 more source
A hybrid mathematical model for self-organizing cell migration in the zebrafish lateral line [PDF]
Journal of Mathematical Biology (2015) 71: 171, 2013 In this paper we propose a "discrete in continuous" mathematical model for the morphogenesis of the posterior lateral line system in zebrafishes. Our model follows closely the results obtained in recent biological experiments. We rely on a hybrid description: discrete for the cellular level and continuous for the molecular level. We prove the existence
arxiv +1 more source
A Novel Long-term, Multi-Channel and Non-invasive Electrophysiology Platform for Zebrafish. [PDF]
, 2016 Zebrafish are a popular vertebrate model for human neurological disorders and drug discovery. Although fecundity, breeding convenience, genetic homology and optical transparency have been key advantages, laborious and invasive procedures are required for
Baraban, Scott C +3 more
core +1 more source