Results 41 to 50 of about 104,138 (249)
Zebrafish, 2008 The secretome is a functionally rich proteome subset, including cellular membrane and extracellular proteins processed through the secretory pathway. In this study, Danio rerio and Homo sapiens RefSeq proteins were analyzed with SignalP, TargetP, Phobius, and pTarget algorithms.
openaire +3 more sources
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Circadian rhythmicity and light sensitivity of the zebrafish brain [PDF]
, 2013 Light is important for entraining circadian rhythms, which regulate a wide range of biological processes. Zebrafish have directly light responsive tissues (Whitmore et al 2000) and are thus a useful vertebrate model for circadian rhythmicity and light ...
Moore, HA
core
Lecithin-Based Dermal Drug Delivery for Anti-Pigmentation Maize Ceramide
Molecules, 2020 Ceramides have several well-known biological properties, including anti-pigmentation and anti-melanogenesis, which make them applicable for use in skincare products in cosmetics. However, the efficacy of ceramides is still limited.
Kazuhiro Kagotani +7 more
doaj +1 more source
Current Opinion in Genetics & Development, 1998 Signals from the organizer play a crucial role in patterning the vertebrate embryo. Recent molecular analysis of zebrafish mutations has established an essential role for BMP2 and chordin in organizer function and has identified one-eyed pinhead as a novel EGF-like gene involved in prechordal plate and endoderm formation.
A F, Schier, W S, Talbot
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The teleost inflammasome as a biosensor in developmental toxicology
Frontiers in ToxicologyIntroductionStandard environmental risk assessment frameworks, such as the OECD 236 Fish Embryo Acute Toxicity (FET) test, rely heavily on macroscopic morphological endpoints that may fail to detect subtle, sublethal molecular disruptions before ...
Darlan Gusso +4 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
On the Observation of Wild Zebrafish (Danio rerio) in India
, 2019 Zebrafish is one of the world's most widely used laboratory species, and it is utilized to answer important research questions in disparate fields such as biomedicine, genetics, developmental biology, pharmacology, toxicology, physiology, and evolution ...
Morgan, Rachael, +5 more
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AnimalsThis work provides a contribution to the understanding of the structure of the photophores in the mesopelagic fish Chauliodus sloani (family Stomiidae), which occasionally are stranded along the coasts of the Strait of Messina (Central Mediterranean Sea).
Mauro Cavallaro +9 more
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