Results 21 to 30 of about 231,505 (286)

Zebra-Fishing for Regenerative Awakening in Mammals

Biomedicines, 2021
Regeneration is defined as the ability to regrow an organ or a tissue destroyed by degeneration or injury. Many human degenerative diseases and pathologies, currently incurable, could be cured if functional tissues or cells could be restored ...
Laura Massoz, Marie Alice Dupont, Isabelle Manfroid   +2 more
doaj   +1 more source

Multi-omics analyses of early liver injury reveals cell-type-specific transcriptional and epigenomic shift

BMC Genomics, 2021
Background Liver fibrosis is a wound-healing response to tissue injury and inflammation hallmarked by the extracellular matrix (ECM) protein deposition in the liver parenchyma and tissue remodelling.
Maciej Migdał, Eugeniusz Tralle, Karim Abu Nahia, Łukasz Bugajski, Katarzyna Zofia Kędzierska, Filip Garbicz, Katarzyna Piwocka, Cecilia Lanny Winata, Michał Pawlak   +8 more
doaj   +1 more source

Magnetosensation in zebrafish [PDF]

Current Biology, 2005
AbstractMany species, from bacteria to vertebrates, have been reported to use the geomagnetic field as a major cue for oriented short and long range migration [1–10], but the molecular nature of the underlying receptor has remained elusive. One of the main reasons may be that past attempts to train animals to respond to magnetic stimuli proved ...
Shcherbakov, Denis, Winklhofer, Michael, Petersen, Nikolai, Steidle, Johannes, Hilbig, Reinhard, Blum, Martin   +5 more
openaire   +2 more sources

Zebrafish in oncology

Aging, 2013
Novel high-throughput technologies generate an unprecedented amount of data, which present a challenge for oncologists aiming to provide personalized treatment. Progress in genetic engineering and xenotransplantation in conjunction with live imaging could establish the zebrafish as one of the most versatile animal models for cancer research.
Barriuso, Jorge; id_orcid 0000-0002-5641-9105, Nagaraju, Raghavendar, Hurlstone, Adam; id_orcid 0000-0001-5260-9457   +2 more
openaire   +2 more sources

Development and automation of a test of impulse control in zebrafish [PDF]

, 2013
Deficits in impulse control (difficulties in inhibition of a pre-potent response) are fundamental to a number of psychiatric disorders, but the molecular and cellular basis is poorly understood.
Straw, C, Ife, Dennis, Dennis eIfe, Caroline Helen Brennan, Mahesh Pancholi, Straw, Chris, Ma, J, Chris Straw, Jun eMa, Parker, Matthew O., Pancholi, M, Ife, D, Parker, MO, Fabrizio eSmeraldi, Smeraldi, Fabrizio, Fabrizio Smeraldi, Matthew O Parker, Mahesh ePancholi, Brennan, Caroline H., Smeraldi, F, Dennis Ife, Chris eStraw, Jun Ma, Ma, Jun, Brennan, CH, Matthew O. Parker, Caroline H. Brennan, Pancholi, Mahesh   +27 more
core   +1 more source

Mapping the m1A, m5C, m6A and m7G methylation atlas in zebrafish brain under hypoxic conditions by MeRIP-seq

BMC Genomics, 2022
Background The epigenetic modifications play important regulatory roles in tissue development, maintenance of physiological functions and pathological process.
Wei Li, Xiaoyu Li, Xunjie Ma, Wei Xiao, Jingjing Zhang   +4 more
doaj   +1 more source

Fluorescent PCR–based Screening Methods for Precise Knock-in of Small DNA Fragments and Point Mutations in Zebrafish

Bio-Protocol, 2023
Generation of zebrafish (Danio rerio) models with targeted insertion of epitope tags and point mutations is highly desirable for functional genomics and disease modeling studies.
Blake Carrington, Raman Sood
doaj   +1 more source

Myocardial protective effect and transcriptome profiling of Naoxintong on cardiomyopathy in zebrafish

Chinese Medicine, 2021
Background Cardiomyopathy is a kind of cardiovascular diseases, which makes it more difficult for the heart to pump blood to other parts of the body, eventually leading to heart failure.
Mengyan Hu, Peirong Liu, Shuxian Lu, Zhihao Wang, Zhaojie Lyu, Hongkai Liu, Yuhong Sun, Feng Liu, Jing Tian   +8 more
doaj   +1 more source

Claudin-5a is essential for the functional formation of both zebrafish blood-brain barrier and blood-cerebrospinal fluid barrier

Fluids and Barriers of the CNS, 2022
Background Mammalian Claudin-5 is the main endothelial tight junction component maintaining blood-brain barrier (BBB) permeability, while Claudin-1 and -3 seal the paracellular space of choroid plexus (CP) epithelial cells contributing to the blood ...
Yanyu Li, Chunchun Wang, Liang Zhang, Bing Chen, Yuqian Mo, Jingjing Zhang   +5 more
doaj   +1 more source

The toxicity of perfluoroalkyl acids in zebrafish (Danio rerio) [PDF]

, 2013
Perfluoroalkyl acids (PFAAs) are globally distributed synthetic chemicals. Their unique properties make them widely used, in industry and elsewhere. These are a group of compounds with varying carbon chain lengths and functional groups.
Ul Haq, Mazhar
core   +1 more source