Results 21 to 30 of about 317,987 (279)

The Zebrafish (Danio rerio) Is a Relevant Model for Studying Sex-Specific Effects of 17β-Estradiol in the Adult Heart [PDF]

open access: yes, 2019
Cardiovascular diseases are a major cause of morbidity and mortality, and there are significant sex differences therein. However, the underlying mechanisms are poorly understood.
Hassel, David   +2 more
core   +1 more source

Myocardial protective effect and transcriptome profiling of Naoxintong on cardiomyopathy in zebrafish

open access: yesChinese Medicine, 2021
Background Cardiomyopathy is a kind of cardiovascular diseases, which makes it more difficult for the heart to pump blood to other parts of the body, eventually leading to heart failure.
Mengyan Hu   +8 more
doaj   +1 more source

Fluorescent PCR–based Screening Methods for Precise Knock-in of Small DNA Fragments and Point Mutations in Zebrafish

open access: yesBio-Protocol, 2023
Generation of zebrafish (Danio rerio) models with targeted insertion of epitope tags and point mutations is highly desirable for functional genomics and disease modeling studies.
Blake Carrington, Raman Sood
doaj   +1 more source

A Zebrafish Model of Mycobacterium leprae Granulomatous Infection. [PDF]

open access: yes, 2017
Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in
Cameron, James   +2 more
core   +2 more sources

A Novel Long-term, Multi-Channel and Non-invasive Electrophysiology Platform for Zebrafish. [PDF]

open access: yes, 2016
Zebrafish are a popular vertebrate model for human neurological disorders and drug discovery. Although fecundity, breeding convenience, genetic homology and optical transparency have been key advantages, laborious and invasive procedures are required for
Baraban, Scott C   +3 more
core   +1 more source

Diagnosis of centrocestus formosanus infection in zebrafish (Danio rerio) in Italy: A window to a new globalization-derived invasive microorganism [PDF]

open access: yes, 2020
Centrocestus formosanus is a digenetic trematode with a complex life cycle, involving invertebrate and vertebrate hosts, humans included. In particular, it causes gill lesions and mortality in freshwater fish species, and gastrointestinal symptoms in ...
Aceto, S.   +9 more
core   +1 more source

Claudin-5a is essential for the functional formation of both zebrafish blood-brain barrier and blood-cerebrospinal fluid barrier

open access: yesFluids and Barriers of the CNS, 2022
Background Mammalian Claudin-5 is the main endothelial tight junction component maintaining blood-brain barrier (BBB) permeability, while Claudin-1 and -3 seal the paracellular space of choroid plexus (CP) epithelial cells contributing to the blood ...
Yanyu Li   +5 more
doaj   +1 more source

The zebrafish xenograft platform-A novel tool for modeling KSHV-associated diseases [PDF]

open access: yes, 2019
Kaposi\u27s sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes.
Berman, Jason N   +12 more
core   +2 more sources

Development of catecholamine and cortisol stress responses in zebrafish. [PDF]

open access: yes, 2014
Both adrenal catecholamines and steroids are known to be involved in the stress response, immune function, blood pressure and energy homeostasis. The response to stress is characterized by the activation of the hypothalamus-pituitary-adrenal (HPA) axis ...
Dipple, Katrina M   +4 more
core   +2 more sources

Calsequestrins in skeletal and cardiac muscle from adult Danio rerio [PDF]

open access: yes, 2015
Calsequestrin (Casq) is a high capacity, low affinity Ca2+-binding protein, critical for Ca2+-buffering in cardiac and skeletal muscle sarcoplasmic reticulum. All vertebrates have multiple genes encoding for different Casq isoforms.
Argenton, Francesco   +6 more
core   +1 more source

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