Results 31 to 40 of about 209,838 (313)

Autophagy in zebrafish

Methods, 2015
From a hitherto underappreciated phenomenon, autophagy has become one of the most intensively studied cellular processes in recent years. Its role in cellular homeostasis, development and disease is supported by a fast growing body of evidence. Surprisingly, only a small fraction of new observations regarding the physiological functions of cellular ...
Máté Varga, Erika Fodor, Tibor Vellai
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Characterization of zebrafish mutants for the emilin2a and emilin2b genes [PDF]

, 2023
reservedLe emiline sono una famiglia di glicoproteine della matrice extracellulare con organizzazione strutturale comune e contenenti un dominio EMI all’N-terminale.
ZORZI, GIULIA
core  

Jagged-mediated lateral induction patterns Notch3 signaling within adult neural stem cell populations

Nature Communications
In the adult brain, Notch3 signaling promotes neural stem cell (NSC) quiescence and stemness. It remains unknown how Notch3 signaling levels are controlled and relate to these NSC decisions.
Sara Ortica, Miguel Martinez Herrera, Louis Degroux, Bastian Rochette, Nicolas Dray, Laure Bally-Cuif   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Circadian rhythmicity and light sensitivity of the zebrafish brain [PDF]

, 2013
Light is important for entraining circadian rhythms, which regulate a wide range of biological processes. Zebrafish have directly light responsive tissues (Whitmore et al 2000) and are thus a useful vertebrate model for circadian rhythmicity and light ...
Moore, HA
core  

On the Observation of Wild Zebrafish (Danio rerio) in India [PDF]

, 2019
Zebrafish is one of the world's most widely used laboratory species, and it is utilized to answer important research questions in disparate fields such as biomedicine, genetics, developmental biology, pharmacology, toxicology, physiology, and evolution ...
Morgan, Rachael,, Sarkar, Kripan,, Sundin, Josefin,, Finnöen, Mette H.,, Dey, Arpita,, Jutfelt, Fredrik,   +5 more
core   +1 more source

The Zebrafish Secretome

Zebrafish, 2008
The secretome is a functionally rich proteome subset, including cellular membrane and extracellular proteins processed through the secretory pathway. In this study, Danio rerio and Homo sapiens RefSeq proteins were analyzed with SignalP, TargetP, Phobius, and pTarget algorithms.
openaire   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Negative cell cycle regulation by calcineurin is necessary for proper beta cell regeneration in zebrafish

eLife
Stimulation of pancreatic beta cell regeneration could be a therapeutic lead to treat diabetes. Unlike humans, the zebrafish can efficiently regenerate beta cells, notably from ductal pancreatic progenitors.
Laura Massoz, David Bergemann, Arnaud Lavergne, Célia Reynders, Caroline Désiront, Chiara Goossens, Lydie Flasse, Bernard Peers, Marianne M Voz, Isabelle Manfroid   +9 more
doaj   +1 more source