Results 11 to 20 of about 231,505 (286)
International Journal of Comparative Psychology, 2017 The purpose and function of sleep has been the topic of discussion for several centuries. Though our understanding of the mechanisms underlying the propagation and maintenance of rest states has undergone significant improvement, much remains to be learned with regards to the effects of disrupted sleep on diseased states.
Echevarria, David J., Khan, Kanza M.
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eLife, 2022 Restoring damaged β-cells in diabetic patients by harnessing the plasticity of other pancreatic cells raises the questions of the efficiency of the process and of the functionality of the new Insulin-expressing cells.
Claudio Andrés Carril Pardo +11 more
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Zebrafish and Flavonoids: Adjuvants against Obesity
Molecules, 2021 Obesity is a pathological condition, defined as an excessive accumulation of fat, primarily caused by an energy imbalance. The storage of excess energy in the form of triglycerides within the adipocyte leads to lipotoxicity and promotes the phenotypic ...
Giuseppe Montalbano +8 more
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Development of a Zebrafish Sepsis Model for High-Throughput Drug Discovery
Molecular Medicine, 2017 Sepsis is a leading cause of death worldwide. Current treatment modalities remain largely supportive. Intervention strategies focused on inhibiting specific mediators of the inflammatory host response have been largely unsuccessful, a consequence of an ...
Anju M. Philip +8 more
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Molecular psychiatry of zebrafish [PDF]
, 2014 Due to their well-characterized neural development and high genetic homology to mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field of biological psychiatry.
Parker, M. O. +14 more
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A phenotypic screen in zebrafish identifies a novel small-molecule inducer of ectopic tail formation suggestive of alterations in non-canonical Wnt/PCP signaling [PDF]
, 2013 Zebrafish have recently emerged as an attractive model for the in vivo bioassay-guided isolation and characterization of pharmacologically active small molecules of natural origin.
Crawford, Alexander D +8 more
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Puromycin-induced kidney injury and subsequent regeneration in adult zebrafish
Animal Cells and Systems, 2023 Puromycin treatment can cause glomerular injury to the kidney, leading to proteinuria. However, the pathogenesis of acute kidney injury and subsequent regeneration after puromycin administration in animal models remain unclear.
Soonil Koun +5 more
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Behaviour and morphology of the zebrafish, danio rerio [PDF]
, 2001 Speciation remains a process that is poorly understood. In particular, little progress has been made in elucidating the mechanisms underlying prezygotic isolation. A full understanding requires a knowledge of underlying genetics.
Pritchard, Victoria Louise
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Frontiers in Integrative Neuroscience, 2011 A key challenge for identifying cellular bases of cognitive functions is to distinguish the contributions of different cell subtypes within complex circuits in a brain. Functional magnetic resonance imaging (fMRI) can reflect what brain areas are activated and electrophysiological recording can record neural activities adjacent to the electrodes, but ...
Ruey-Kuang eCheng +4 more
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The role of zebrafish (Danio rerio) in dissecting the genetics and neural circuits of executive function [PDF]
, 2013 Zebrafish have great potential to contribute to our understanding of behavioural genetics and thus to contribute to our understanding of the aetiology of psychiatric disease.
Brock, AJ +15 more
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