Results 61 to 70 of about 209,838 (313)

Natterin bridges IFN-φ1 and non-canonical inflammasome pathways via CRFB1/Gbp4 to license Caspy2-mediated antibacterial immunity

open access: yesFrontiers in Cellular and Infection Microbiology
The Natterin protein family represents an evolutionarily conserved group of immune effectors in teleosts, yet its broader regulatory role in host defense remains poorly understood.
Darlan Gusso   +6 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

An in vivo study of signaling pathways involved in zebrafish thyroid formation. [PDF]

open access: yes, 2013
The molecular pathways contributing to thyroid development and function appear to be highly conserved in vertebrates; similar to mammals, the zebrafish thyroid gland is composed of endoderm-derived follicles, filled with colloid and producing thyroid ...
G. Marchetto   +16 more
core  

Morphological and Immunohistochemical Study of Ventral Photophores of Ichthyococcus ovatus (Cocco, 1838) (Fam: Stomiidae)

open access: yesJournal of Marine Science and Engineering
Photophores are light-producing organs found in many fish species living in the mesopelagic, bathypelagic, and abyssal layers of the ocean. They function to attract prey, confuse predators, and communicate with other individuals of the same species ...
Mauro Cavallaro   +8 more
doaj   +1 more source

Conserved and Divergent Features of Adult Neurogenesis in Zebrafish

open access: yesFrontiers in Cell and Developmental Biology, 2020
Adult neurogenesis, i.e., the generation of neurons from neural stem cells (NSCs) in the adult brain, contributes to brain plasticity in all vertebrates.
Miriam Labusch   +6 more
doaj   +1 more source

Role of Extracellular Mycobacteria in Blood-Retinal Barrier Invasion in a Zebrafish Model of Ocular TB

open access: yesPathogens, 2021
Intraocular inflammation following mycobacterial dissemination to the eye is common in tuberculosis (TB)-endemic countries. However, the early host–pathogen interactions during ocular dissemination are unknown.
Santhosh Kumar Damera   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

The interaction of Notch signalling, haemodynamic flow and angiogenesis in Von Hippel-Lindau mutant zebrafish. [PDF]

open access: yes, 2013
Introduction: There is increasing evidence that the endothelium is able to transduce circulatory force into signals which influence angiogenic behaviour.
Watson, Oliver
core  

Characterization of Intracellular Peptides from Zebrafish (Danio rerio) Brain [PDF]

open access: yes, 2019
Brazilian National Research CouncilFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Brazilian National Research Council: 449390/2014-4Processo FAPESP: 2015/22752-0Processo FAPESP: 2016/04000-3Processo FAPESP: 2013/07467-0Peptides represent a ...
Correa, Claudia Neves   +7 more
core   +1 more source

Zebrafish as an Integrative Model for Central Nervous System Research: Current Advances and Translational Perspectives

open access: yesLife
Central nervous system disorders represent a heterogeneous set of conditions triggered by genetic alterations, environmental exposures, infections, injuries, and even iatrogenic causes.
Lidia Pansera   +9 more
doaj   +1 more source

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