Results 61 to 70 of about 209,207 (313)

Natterin bridges IFN-φ1 and non-canonical inflammasome pathways via CRFB1/Gbp4 to license Caspy2-mediated antibacterial immunity

Frontiers in Cellular and Infection Microbiology
The Natterin protein family represents an evolutionarily conserved group of immune effectors in teleosts, yet its broader regulatory role in host defense remains poorly understood.
Darlan Gusso, Felipe Justiniano Pinto, Aline Ingrid Andrade-Barros, Jefferson Thiago Gonçalves Bernardo, Carlos DeOcesano-Pereira, Monica Lopes-Ferreira, Carla Lima   +6 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The interaction of Notch signalling, haemodynamic flow and angiogenesis in Von Hippel-Lindau mutant zebrafish. [PDF]

, 2013
Introduction: There is increasing evidence that the endothelium is able to transduce circulatory force into signals which influence angiogenic behaviour.
Watson, Oliver
core  

Zebrafish as an Integrative Model for Central Nervous System Research: Current Advances and Translational Perspectives

Life
Central nervous system disorders represent a heterogeneous set of conditions triggered by genetic alterations, environmental exposures, infections, injuries, and even iatrogenic causes.
Lidia Pansera, Kamel Mhalhel, Mauro Cavallaro, Marialuisa Aragona, Rosaria Laurà, Maria Levanti, Maria Cristina Guerrera, Francesco Abbate, Antonino Germanà, Giuseppe Montalbano   +9 more
doaj   +1 more source

Temporal Variations of CAT, GSH, and LPO in Gills and Livers of Zebrafish, Danio Rerio, Exposed to Dimethoate

Archives of Polish Fisheries, 2014
Pesticides are designed to kill a very wide range of undesirable organisms, but they simultaneously adversely affect non-target organisms in ecosystems.
Ansari Shabnam, Ansari Badre Alam
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Connectivity, plasticity, and function of neuronal circuits in the zebrafish olfactory forebrain [PDF]

, 2014
For most living animals such as worms, insects, fishes, rodents and humans, chemical cues from the environment (odorants) play critical roles in guiding behaviors important for survival, including preying, mating, breeding, and escaping.
Zou, Ming
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source