Results 61 to 70 of about 231,505 (286)
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Study of the role of the transcription factor Pax6b and different signaling pathways on pancreas differentiation in zebrafish (Danio rerio) [PDF]
, 2013 The developmental dynamics of the zebrafish pancreas are highly similar to mammals: the organ arises from a ventral and a dorsal bud (Field et al., 2003), and the endocrine compartment produces all different hormones: insulin, glucagon, somatostatin ...
B. Peers +12 more
core
LifeCentral nervous system disorders represent a heterogeneous set of conditions triggered by genetic alterations, environmental exposures, infections, injuries, and even iatrogenic causes.
Lidia Pansera +9 more
doaj +1 more source
Archives of Polish Fisheries, 2014 Pesticides are designed to kill a very wide range of undesirable organisms, but they simultaneously adversely affect non-target organisms in ecosystems.
Ansari Shabnam, Ansari Badre Alam
doaj +1 more source
Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma. [PDF]
Animal Model Exp MedA zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Chen L +11 more
europepmc +2 more sources
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Perspectives in Zebrafish Research
, 2020 In the past decade, a small tropical vertebrate fish, zebrafish, has rapidly gained the interest of research laboratories worldwide as a model system. This topic will provide updated perspectives on all fields of zebrafish research from experts gathering
core +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
The Zebrafish Sperm Proteome [PDF]
PROTEOMICSABSTRACT One of the key processes that forms the basis of fertilisation is the tight interaction between sperm and egg. Both sperm and egg proteomes are known to evolve and diverge rapidly even between closely related species.
Jayme Cohen-Krais +9 more
openaire +3 more sources