Results 71 to 80 of about 419,255 (408)
Editorial: Zebrafish Epigenetics
A key area of focus in the field of epigenetics pertains the comprehension of the functional relevance of the epigenetic mechanisms occurring during embryogenesis to shape normal developmental trajectories and adult phenotypes (Atlasi and Stunnenberg, 2017; Skvortsova et al., 2018; Cavalieri, 2021; Marchione et al., 2021).
Vincenzo Cavalieri+2 more
openaire +4 more sources
Pesticides are designed to kill a very wide range of undesirable organisms, but they simultaneously adversely affect non-target organisms in ecosystems.
Ansari Shabnam, Ansari Badre Alam
doaj +1 more source
Conserved and Divergent Features of Adult Neurogenesis in Zebrafish
Adult neurogenesis, i.e., the generation of neurons from neural stem cells (NSCs) in the adult brain, contributes to brain plasticity in all vertebrates.
Miriam Labusch+6 more
doaj +1 more source
Brownian-like deviation of neighboring cells in the early embryogenesis of the zebrafish [PDF]
We investigate cell trajectories during zebrafish early embryogenesis based on 3D+time photonic microscopy imaging data. To remove the collective flow motion and focus on fluctuations, we analyze the deviations of pairs of neighboring cells. These deviations resemble Brownian motion and reveal different behaviors between pairs containing daughter cells
arxiv +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Knowledge about the genetic pathways that control nephron development is essential for better understanding the basis of congenital malformations of the kidney.
Bridgette E. Drummond+10 more
doaj +1 more source
Characterization of Expression of the KCNE Gene Family in Zebrafish, Danio rerio [PDF]
The KCNE gene family codes for five transmembrane accessory proteins, minK related peptides or Mirps, involved in the modification of voltage-gated potassium (Kv) channels, K+ selective pores vital in the regulation of membrane potential and ...
Vernlund, Lauren
core +1 more source
High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]
BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E.+12 more
core +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
What is the Thalamus in Zebrafish? [PDF]
Current research on the thalamus and related structures in the zebrafish diencephalon identifies an increasing number of both neurological structures and ontogenetic processes as evolutionary conserved between teleosts and mammals. The patterning processes, for example, which during the embryonic development of zebrafish form the thalamus proper appear
openaire +5 more sources