Results 41 to 50 of about 266,614 (289)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Phase-to-phase power balance control in flexible interconnection equipment by injecting zero sequence voltage

Xi'an Gongcheng Daxue xuebao
The multi terminal flexible interconnection equipment with cascaded full bridge and dual active bridge structure could connect AC power grid and multiple DC power grid, and instantaneous power differences in different DC power grids and sub module faults
WANG Bo, JI Ziyue, WANG Wanxing, XIAO Chaomin, ZHANG Yan   +4 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Position estimation delays in signal injection-based sensorless PMSM drives [PDF]

, 2012
The causes of position estimation delays and their effects on the sensorless control of permanent magnet synchronous motor drives are investigated. The position of a permanent magnet synchronous machine is estimated via the injection of high frequency ...
Altomare, A., Cupertino, F., Guagnano, A., Pellegrino, Gian-Mario Luigi   +3 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Flexible control for power‐sharing in the CHB‐based SST under voltage unbalance conditions

IET Power Electronics, 2021
Solid‐state transformers (SSTs) have flexible capabilities to improve the power quality issues. These improvements impose disturbances into the SST converters that require proper control algorithms. In this paper, the problems of the unequal active power
Mehdi Babaei, Reza Ghandehari
doaj   +1 more source

Turn-to-turn fault protection technique for synchronous machines without additional voltage transformers [PDF]

, 2017
This paper presents a novel protection technique for the detection of inter-turn faults in synchronous machines. It is based on the calculation of voltage in the stator windings from the usual phases and neutral voltage, typically available in ...
Gyftakis, Konstantinos N., Platero , Carlos A., Redondo, Marte   +2 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Power quality improvement by grid-connected inverters driven by the three-phase damping control strategy operated in different modes

International Journal of Electrical Power & Energy Systems
The increased demand for renewable energy and electrification of transportation such as electric vehicles can lead to power quality problems in the low voltage distribution grids.
Dimitar V. Bozalakov, Sajid Qazi, Jeroen D.M. De Kooning, Lieven Vandevelde   +3 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source