Results 111 to 120 of about 20,825 (172)

Nanoparticles in HIV treatment for improved drug delivery, clinical translation, and future direction. [PDF]

open access: yesDiscov Nano
Terkimbi SD   +5 more
europepmc   +1 more source

Persistent Seronegativity and Absence of Intact Proviruses Despite Prolonged Initial Viremia in Early-Treated Perinatal HIV Infection. [PDF]

open access: yesOpen Forum Infect Dis
Charre C   +10 more
europepmc   +1 more source
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Metabolism of zidovudine

General Pharmacology: The Vascular System, 1995
1. The anti-HIV drug zidovudine (3'-azido-2',3'-dideoxythymidine; ZDV) has three important pathways of metabolism. ZDV is a prodrug and must be phosphorylated in lymphocytes in order to exert its antiviral action. However, in quantitative terms this is a minor pathway probably accounting for less than 1% of the overall metabolic profile.
G J, Veal, D J, Back
openaire   +2 more sources

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