Human Deoxycytidine Kinase Is a Valuable Biocatalyst for the Synthesis of Nucleotide Analogues [PDF]
Natural ribonucleoside-5’-monophosphates are building blocks for nucleic acids which are used for a number of purposes, including food additives. Their analogues, additionally, are used in pharmaceutical applications.
Hellendahl, Katja F. +4 more
core +1 more source
INTRODUCTION: Although combined Anti-Retroviral Therapy (cART) has improved the quality of life and survival in people living with HIV-AIDS (PLWHA), there have been reports of increased non-AIDS related co-morbidities such as coagulopathies.
Richard Kobina Dadzie Ephraim +6 more
doaj +1 more source
Reviewing progress: 7 Year Trends in Characteristics of Adults and Children Enrolled at HIV Care and Treatment Clinics in the United Republic of Tanzania. [PDF]
To evaluate the on-going scale-up of HIV programs, we assessed trends in patient characteristics at enrolment and ART initiation over 7 years of implementation. Data were from Optimal Models, a prospective open cohort study of HIV-infected (HIV+) adults (
A Anema +50 more
core +3 more sources
This study evaluated the clastogenic and/or aneugenic potential of three nucleoside reverse transcriptase inhibitors (zidovudine - AZT, lamivudine - 3TC and stavudine - d4T) using the cytokinesis-block micronucleus (CBMN) assay in human lymphocyte ...
Eloir D. Lourenço +7 more
doaj
Chemical and Toxicological Analysis of Antiretroviral Drugs
Introduction. Human Immunodeficiency Virus (HIV) is one of the main socially significant infection all over the world. HIV-positive patients take medical care, including antiretroviral drugs (ARVs) pharmacotherapy.
T. N. Komarov +7 more
doaj +1 more source
Yemane Berhane,1 Diresibachew Haile,2 Tesfaye Tolessa2 1Department of Biomedical Science, College of Medicine and Health Science, Adigrat University, Adigrat, Northern Ethiopia, Ethiopia; 2Department of Medical Physiology, School of Medicine, College of ...
Berhane Y, Haile D, Tolessa T
doaj
Promoting adherence to antiretroviral therapy: the experience from a primary care setting in Khayelitsha, South Africa. [PDF]
OBJECTIVE: To describe the approach used to promote adherence to antiretroviral therapy (ART) and to present the outcomes in the first primary care public sector ART project in South Africa.
Asselman, V +5 more
core +1 more source
Genotype and Phenotype at Baseline and at Failure in Human Immunodeficiency Virus–Infected Antiretroviral‐Naive Patients in a Randomized Trial Comparing Zidovudine and Lamivudine plus Nelfinavir or Nevirapine [PDF]
Elena Ferrer +11 more
openalex +1 more source
Hair Zidovudine Concentrations Predict Virologic Outcomes Among People Living with HIV/AIDS in China
Yan Wu,1– 3,* Shuaifeng Liu,4,* Liuxi Chu,1– 3 Quan Zhang,5,6 Jin Yang,3,7 Shan Qiao,5 Xiaoming Li,5 Yuejiao Zhou,4 Huihua Deng,1– 3 Zhiyong Shen4 1Department of Brain and Learning Science, School of Biological Science & Medical Engineering ...
Wu Y +9 more
doaj
Electrochemical and Spectrometric Study of GFP-AZT Interaction
In the last 18 years the highly active antiretroviral therapy (HAART) has been used for the treatment of HIV and consists of the combination of various drugs.
Ondrej Zitka +7 more
doaj +1 more source

