Results 131 to 140 of about 82,709 (254)
Cross‐Reactive Neutralizing Antibodies Between ZIKV and DENV May Exhibit Serotype Specificity
Graphical Abstract and Lay Summary Immunization with ZIKV protein extract may induce serotype‐specific neutralizing antibodies against DENV. ABSTRACT Dengue virus (DENV) and Zika virus (ZIKV) are public health threats, causing substantial morbidity and mortality worldwide.
Lucimeire Antonelli da Silveira +7 more
wiley +1 more source
The cross‐validated regression tree showed modest predictive performance. Mortality was not significantly associated with the first two PCA axes. Molecular modeling generated testable ligand–target hypotheses. Psidium cattleianum had lower LD50. The larvicidal activity of the crude extracts could not be attributed to individual constituents.
Ubiratan Alegransi Bones +8 more
wiley +1 more source
This study investigates the essential oil composition of E. paniculata wood, bark, and leaves by GC–MS. Biological evaluations of the leaf essential oil reveal promising larvicidal potential against Aedes aegypti and in vitro inhibitory activities against α‐glucosidase and acetylcholinesterase (AChE), supported by molecular docking simulations ...
Jenifer Priscila de Araujo +13 more
wiley +1 more source
Short‐Chain Fatty Acids: Microbial Metabolites Driving Gut‐Eye Axis Signaling
Short‐chain fatty acids generated by gut microbial fermentation link diet to ocular physiology via the gut–eye axis. Through systemic distribution, these metabolites regulate GPCR signaling, epigenetic pathways, inflammation, and angiogenesis, shaping retinal homeostasis and highlighting therapeutic potential in ocular vascular and inflammatory ...
Aleah J. Brokemond +6 more
wiley +1 more source
Dengue, chikungunya, Virus de Zika. Determinantes sociales
RESUMEN El dengue, chikungunya y zika son enfermedades del grupo de las arbovirosis, transmitidas por los mosquitos Aedes aegypti y Aedes albopictus.
María del Carmen Álvarez Escobar +4 more
doaj
This review summarises the detection methods for severe fever with thrombocytopenia syndrome virus based on CRISPR platforms. (A) CRISPR with fluorescent reporter. (B) CRISPR with lateral flow test strip. (C) CRISPR with DNAzyme. (D) Digital CRISPR. (E) CRISPR with single micro‐ring resonator biosensor. (F) self‐amplifying signal amplification strategy
Junhu Wang +8 more
wiley +1 more source
Organoids: Current Applications and Future Directions
Organoids are three‐dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering have established organoids as powerful platforms for studying human development and disease mechanisms, drug ...
Yueqi Leng +14 more
wiley +1 more source
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley +1 more source
Zika virus PlatformQHealth [PDF]
Slides from "a CDC update for clinicians on Zika Virus disease" at IDCareLive.Dr. Joanne Cono, MD, ScM, Director of the Office of Science Quality of the CDC gave a live presentation regarding the latest Zika information available and answered a myriad of
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Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source

