Results 141 to 150 of about 127,215 (250)
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Dengue, chikungunya, Virus de Zika. Determinantes sociales
RESUMEN El dengue, chikungunya y zika son enfermedades del grupo de las arbovirosis, transmitidas por los mosquitos Aedes aegypti y Aedes albopictus.
María del Carmen Álvarez Escobar +4 more
doaj
Discovery, evolution and potential future applications of bismuth bicycle molecules—a novel class of therapeutics with unique properties. ABSTRACT Bicyclic peptides are emerging as next generation therapeutics by combining the affinity and specificity of antibodies with the synthetic convenience of small molecules.
Saan Voss +8 more
wiley +1 more source
Abstract Objectives The COVID‐19 pandemic affected mental health worldwide, including obsessive‐compulsive symptoms (OCS) and, specifically, contamination‐related OCS (C‐OCS). This study aimed to map these symptoms' trajectories over four years, thus providing the longest known observational timeline of OCS during and after a pandemic.
Lea Schuurmans +5 more
wiley +1 more source
Description of Hip Deformities in 5-Year-Old Patients with Congenital Zika Virus Syndrome. [PDF]
Kleebayoon A, Wiwanitkit V.
europepmc +2 more sources
Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe +2 more
wiley +1 more source
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee +9 more
wiley +1 more source
Reply to the Letter to the Editor Regarding "Description of Hip Deformities in 5-Year-Old Patients with Congenital Zika Virus Syndrome: A Cross-Sectional Study". [PDF]
Oliveira HFV +5 more
europepmc +2 more sources
RIMSKA DRŽAVNO-PRAVNA TRADICIJA U KONTEKSTU EVROPSKIH INTEGRACIJA SRBIJE
Žika Bujuklić
doaj +1 more source
In dem Beitrag werden die Beschäftigungseffekte der Neufassung des Entgeltfortzahlungsgesetzes mit Hilfe der IAB/Westphal-Version des makroökonomischen SYSIFO-Modells simuliert.
Zika, Gerd
core

