Results 141 to 150 of about 127,215 (250)

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Dengue, chikungunya, Virus de Zika. Determinantes sociales

open access: yesRevista Médica Electrónica
RESUMEN El dengue, chikungunya y zika son enfermedades del grupo de las arbovirosis, transmitidas por los mosquitos Aedes aegypti y Aedes albopictus.
María del Carmen Álvarez Escobar   +4 more
doaj  

Bismuth Bicycles

open access: yesJournal of Peptide Science, Volume 32, Issue 3, March 2026.
Discovery, evolution and potential future applications of bismuth bicycle molecules—a novel class of therapeutics with unique properties. ABSTRACT Bicyclic peptides are emerging as next generation therapeutics by combining the affinity and specificity of antibodies with the synthetic convenience of small molecules.
Saan Voss   +8 more
wiley   +1 more source

Echoes of ease: Tracing the course of obsessive‐compulsive symptoms in the aftermath of a pandemic—Insights from a four‐year panel study

open access: yesBritish Journal of Clinical Psychology, Volume 65, Issue 1, Page 236-249, March 2026.
Abstract Objectives The COVID‐19 pandemic affected mental health worldwide, including obsessive‐compulsive symptoms (OCS) and, specifically, contamination‐related OCS (C‐OCS). This study aimed to map these symptoms' trajectories over four years, thus providing the longest known observational timeline of OCS during and after a pandemic.
Lea Schuurmans   +5 more
wiley   +1 more source

Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe   +2 more
wiley   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 6, 9 February 2026.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

Mehr Beschäftigung durch eingeschränkte Lohnfortzahlung im Krankheitsfall? Modellrechnungen des IAB zu den Arbeitsmarktwirkungen der Änderung des Entgeltfortzahlungsgesetzes

open access: yes, 1997
In dem Beitrag werden die Beschäftigungseffekte der Neufassung des Entgeltfortzahlungsgesetzes mit Hilfe der IAB/Westphal-Version des makroökonomischen SYSIFO-Modells simuliert.
Zika, Gerd
core  

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