Cost-effectiveness of a potential Zika vaccine candidate: a case study for Colombia [PDF]
Background: A number of Zika vaccine platforms are currently being investigated, some of which have entered clinical trials. We sought to evaluate the cost-effectiveness of a potential Zika vaccine candidate under the WHO Vaccine Target Product Profile ...
Moghadas, Seyed +2 more
core +2 more sources
Intracellular Interactions Between Arboviruses and Wolbachia in Aedes aegypti
Aedes aegypti is inherently susceptible to arboviruses. The geographical expansion of this vector host species has led to the persistence of Dengue, Zika, and Chikungunya human infections.
Jerica Isabel L. Reyes +9 more
doaj +1 more source
Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques. [PDF]
Zika virus (ZIKV) is a mosquito-transmitted virus that can cause severe defects in an infected fetus. ZIKV is also transmitted by sexual contact, although the relative importance of sexual transmission is unclear.
Busch, Michael +11 more
core +1 more source
In vivo imaging of Zika virus reveals dynamics of viral invasion in immune-sheltered tissues and vertical propagation during pregnancy [PDF]
Rationale: Zika virus (ZIKV) is a pathogenic virus known to cause a wide range of congenital abnormalities, including microcephaly, Guillain-Barre syndrome, meningoencephalitis, and other neurological complications, in humans. This study investigated the
Hu, Q +12 more
core +1 more source
Zika virus and the never-ending story of emerging pathogens and transfusion medicine [PDF]
In the last few years, the transfusion medicine community has been paying special attention to emerging vector-borne diseases transmitted by arboviruses.
Grazzini, Giuliano +4 more
core +1 more source
Here, we transform this otherwise destructive enzymatic activity into a powerful diagnostic advantage through an RNase I–assisted rolling circle amplification (RI‐RCA) strategy. By integrating controlled RNase I–mediated RNA digestion with circular DNA templates, this approach enables direct and highly sensitive detection of target RNA sequences. Using
Amal Mathai +5 more
wiley +2 more sources
Zika virus infection reprograms global transcription of host cells to allow sustained infection. [PDF]
Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection.
Bansal, Vikas +5 more
core +2 more sources
Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]
Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T +11 more
core +1 more source
Zika; A Threat to Making Important Decisions on Maternal and Perinatal Health
The Zika virus disease represents a great challenge for the medical-scientific community not only because of the association that exists with microcephaly and other congenital anomalies, but also because of the presence of confirmed cases of congenital ...
Reynoso Vázquez Josefina +5 more
doaj +1 more source
Microcephaly: Significance and how to approach during the zika era [PDF]
Microcephaly is an uncommon but important ultrasonographic finding. The smallest-head infants trend to suffer the severest level of developmental delay.
Tharangrut Hanprasertpong
doaj +1 more source

