Results 51 to 60 of about 78,106 (261)
Saudi Medical Journal, 2016 [No Abstract Available].
Marina Molenaar-Hoogendijk +2 more
openaire +3 more sources
Zika virus protection by a single low dose nucleoside modified mRNA vaccination
Nature, 2017 Zika virus (ZIKV) has recently emerged as a pandemic associated with severe neuropathology in newborns and adults. There are no ZIKV-specific treatments or preventatives.
N. Pardi +36 more
semanticscholar +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Zika virus in the Americas: Early epidemiological and genetic findings
Science, 2016 Zika virus genomes from Brazil The Zika virus outbreak is a major cause for concern in Brazil, where it has been linked with increased reports of otherwise rare birth defects and neuropathology. In a phylogenetic analysis, Faria et al.
N. Faria +56 more
semanticscholar +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Zika; A Threat to Making Important Decisions on Maternal and Perinatal Health
Journal of Pure and Applied Microbiology, 2019 The Zika virus disease represents a great challenge for the medical-scientific community not only because of the association that exists with microcephaly and other congenital anomalies, but also because of the presence of confirmed cases of congenital ...
Reynoso Vázquez Josefina +5 more
doaj +1 more source
Microcephaly: Significance and how to approach during the zika era [PDF]
Thai Journal of Obstetrics and Gynaecology, 2017 Microcephaly is an uncommon but important ultrasonographic finding. The smallest-head infants trend to suffer the severest level of developmental delay.
Tharangrut Hanprasertpong
doaj +1 more source
The Lancet, 2016 Background The emergence of Zika virus (ZIKV) in the Americas has coincided with an increase in the report of birth of infants with microcephaly. On 1 February 2016, the World Health Organization declared the suspected link between ZIKV and microcephaly ...
S. Cauchemez +11 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Can Zika Virus Infection in High Risk Pregnant Women Be Differentiated on the Basis of Symptoms?
Viruses, 2020 Zika virus (ZIKV) infection in pregnancy is associated with congenital neurological abnormalities. Our understanding of the full clinical spectrum of ZIKV infection is incomplete.
Nuria Sanchez Clemente +5 more
doaj +1 more source