Results 61 to 70 of about 128,863 (254)
Synthesis of 4′-Substituted-2′-Deoxy-2′-α-Fluoro Nucleoside Analogs as Potential Antiviral Agents
Nucleoside analogs are widely used for the treatment of viral diseases (Hepatitis B/C, herpes and human immunodeficiency virus, HIV) and various malignancies.
Mahesh Kasthuri +8 more
doaj +1 more source
Experimental Zika Virus Infection in the Pregnant Common Marmoset Induces Spontaneous Fetal Loss and Neurodevelopmental Abnormalities. [PDF]
During its most recent outbreak across the Americas, Zika virus (ZIKV) was surprisingly shown to cause fetal loss and congenital malformations in acutely and chronically infected pregnant women.
Aagaard, Kjersti M +17 more
core +2 more sources
Zika and Flavivirus Shell Disorder: Virulence and Fetal Morbidity
Zika virus (ZIKV) was first discovered in 1947 in Africa. Since then, sporadic ZIKV infections of humans have been reported in Africa and Asia. For a long time, this virus was mostly unnoticed due to its mild symptoms and low fatality rates.
Gerard Kian-Meng Goh +3 more
doaj +1 more source
Prevention and control of Zika fever as a mosquito-borne and sexually transmitted disease
The ongoing Zika virus (ZIKV) epidemic poses a major global public health emergency. It is known that ZIKV is spread by \textit{Aedes} mosquitoes, recent studies show that ZIKV can also be transmitted via sexual contact and cases of sexually transmitted ...
Chowell, G +7 more
core +1 more source
Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses [PDF]
The recent outbreak of infection with Zika virus (ZIKV; Flaviviridae) has attracted attention to this previously neglected mosquito-borne pathogen and the need for efficient therapies.
Donald, Claire L. +4 more
core +1 more source
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos +8 more
wiley +1 more source
The symptoms of Zika virus infection may last up to one week and include a maculopapular rash, fever, joint and muscle pain, and conjunctivitis.[1][1],[2][2] Previous outbreaks in the Pacific Islands and the current outbreak have indicated a potential association with neurologic illnesses such ...
Derek R, MacFadden, Isaac I, Bogoch
openaire +2 more sources
Recent increases in infectious diseases affecting the central nervous system have raised concerns about their role in neuroinflammation and neurodegeneration.
Raíssa Leite-Aguiar +4 more
doaj +1 more source
Introduction: arbovirus infections are a serious health problem in Peru. Higher population awareness and their participation in preventive activities can minimize their impact.
Cinthya Yanina Santa Cruz-López +3 more
doaj
Detecting extirpation: A localized approach to a global problem
The global biodiversity crisis stems from a cascading series of extirpations driving species toward extinction. Addressing this crisis requires methods for early detection of extinction at local scales, where communities can mobilize conservation efforts.
Andrew D. F. Simon +4 more
wiley +1 more source

