Results 61 to 70 of about 128,863 (254)

Synthesis of 4′-Substituted-2′-Deoxy-2′-α-Fluoro Nucleoside Analogs as Potential Antiviral Agents

open access: yesMolecules, 2020
Nucleoside analogs are widely used for the treatment of viral diseases (Hepatitis B/C, herpes and human immunodeficiency virus, HIV) and various malignancies.
Mahesh Kasthuri   +8 more
doaj   +1 more source

Experimental Zika Virus Infection in the Pregnant Common Marmoset Induces Spontaneous Fetal Loss and Neurodevelopmental Abnormalities. [PDF]

open access: yes, 2018
During its most recent outbreak across the Americas, Zika virus (ZIKV) was surprisingly shown to cause fetal loss and congenital malformations in acutely and chronically infected pregnant women.
Aagaard, Kjersti M   +17 more
core   +2 more sources

Zika and Flavivirus Shell Disorder: Virulence and Fetal Morbidity

open access: yesBiomolecules, 2019
Zika virus (ZIKV) was first discovered in 1947 in Africa. Since then, sporadic ZIKV infections of humans have been reported in Africa and Asia. For a long time, this virus was mostly unnoticed due to its mild symptoms and low fatality rates.
Gerard Kian-Meng Goh   +3 more
doaj   +1 more source

Prevention and control of Zika fever as a mosquito-borne and sexually transmitted disease

open access: yes, 2016
The ongoing Zika virus (ZIKV) epidemic poses a major global public health emergency. It is known that ZIKV is spread by \textit{Aedes} mosquitoes, recent studies show that ZIKV can also be transmitted via sexual contact and cases of sexually transmitted ...
Chowell, G   +7 more
core   +1 more source

Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses [PDF]

open access: yes, 2017
The recent outbreak of infection with Zika virus (ZIKV; Flaviviridae) has attracted attention to this previously neglected mosquito-borne pathogen and the need for efficient therapies.
Donald, Claire L.   +4 more
core   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos   +8 more
wiley   +1 more source

Zika virus infection [PDF]

open access: yesCanadian Medical Association Journal, 2016
The symptoms of Zika virus infection may last up to one week and include a maculopapular rash, fever, joint and muscle pain, and conjunctivitis.[1][1],[2][2] Previous outbreaks in the Pacific Islands and the current outbreak have indicated a potential association with neurologic illnesses such ...
Derek R, MacFadden, Isaac I, Bogoch
openaire   +2 more sources

Extracellular nucleotides mediate viral central nervous system infections: Key alarmins of neuroinflammation and neurodegeneration

open access: yesNeural Regeneration Research
Recent increases in infectious diseases affecting the central nervous system have raised concerns about their role in neuroinflammation and neurodegeneration.
Raíssa Leite-Aguiar   +4 more
doaj   +1 more source

Knowledge and preventive measures on arbovirus infections among university students in an endemic area of Peru

open access: yesRevista Información Científica, 2022
Introduction: arbovirus infections are a serious health problem in Peru. Higher population awareness and their participation in preventive activities can minimize their impact.
Cinthya Yanina Santa Cruz-López   +3 more
doaj  

Detecting extirpation: A localized approach to a global problem

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
The global biodiversity crisis stems from a cascading series of extirpations driving species toward extinction. Addressing this crisis requires methods for early detection of extinction at local scales, where communities can mobilize conservation efforts.
Andrew D. F. Simon   +4 more
wiley   +1 more source

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