Results 61 to 70 of about 78,106 (261)
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
Advanced Science, EarlyView.ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
Letters in Biomathematics, 2019 Zika is a vector borne disease for which the latest world wide outbreak inspired a renewed interest in epidemiological modelling of vector borne diseases.
S. Bañuelos +3 more
doaj +1 more source
Revista Peruana de Medicina Experimental y Salud Pública, 2019 Objetivos. Determinar la proporción de microcefalia en recién nacidos en establecimientos de salud (EESS) de nivel II y III del Ministerio de Salud (MINSA) de Perú durante el periodo 2005-2013. Materiales y métodos.
Gabriela Santos-Antonio +6 more
doaj +1 more source
First report of autochthonous transmission of Zika virus in Brazil
Memórias do Instituto Oswaldo Cruz, 2015 In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil.
C. Zanluca +5 more
semanticscholar +1 more source
Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation
Advanced Science, EarlyView.Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang +4 more
wiley +1 more source
Sexual and Reproductive Health Matters, 2019 Since the beginning of the Zika virus epidemic, the Brazilian Ministry of Health has reported over 2000 confirmed cases of microcephaly associated with Zika virus in Brazil, with the cases concentrated in the northeast states.
Kimberly Gressick +2 more
doaj +1 more source
Microcefalia por Zika un problema latente: Reporte de Caso y Aspectos Moleculares
Infectio, 2020 We present the case of a 20-day-old patient from Cartagena (Bolívar), hospitalized for presenting a 6-day fever associated with respiratory symptoms with normal neurological evaluation. The obstetric ultrasound showed a microcephaly with a percentile of
Oscar Patiño
doaj +1 more source
A Mouse Model of Zika Virus Pathogenesis
Cell Host and Microbe, 2016 SUMMARY Due to the ongoing Zika virus (ZIKV) epidemic and unexpected clinical outcomes including Guillain-Barré syndrome and birth defects, there is an urgent need for animal model development.
Helen M. Lazear +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu +7 more
wiley +1 more source
Importance of Zika Virus NS5 Protein for Viral Replication
Pathogens, 2019 Zika virus is the latest addition to an ever-growing list of arboviruses that are causing outbreaks with serious consequences. A few mild cases were recorded between 1960 and 1980 until the first major outbreak in 2007 on Yap Island. This was followed by
Hesham Elshahawi +2 more
doaj +1 more source