Results 81 to 90 of about 78,106 (261)

Knowledge and preventive measures on arbovirus infections among university students in an endemic area of Peru

open access: yesRevista Información Científica, 2022
Introduction: arbovirus infections are a serious health problem in Peru. Higher population awareness and their participation in preventive activities can minimize their impact.
Cinthya Yanina Santa Cruz-López   +3 more
doaj  

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

open access: yesChemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier   +7 more
wiley   +1 more source

Synthesis and Biological Activity of Fe (III) Acetate for Microbial Control at Breeding Sites of Aedes aegypti (Diptera: Culicidae)

open access: yesOrbital: The Electronic Journal of Chemistry, 2018
Unconventional approaches can be used control populations of disease-carrying insect to improve health, economic, social, and environmental standards. There is a need for prolonged reduction of vector populations, using low-toxicity and low-cost products
Jéssica Verger Nardeli   +6 more
doaj   +1 more source

High Seroprevalence of Antibodies against Arboviruses among Pregnant Women in Rural Caribbean Colombia in the Context of the Zika Virus Epidemic

open access: yesAntibodies, 2020
Mosquito-borne viruses such as dengue (DENV), chikungunya (CHIKV), and Zika (ZIKV) have spread in recent decades. We aimed to assess seroprevalence of arboviral infections in pregnant women living in Cereté, Caribbean Colombia.
Elena Marbán-Castro   +6 more
doaj   +1 more source

Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing

open access: yesExploration, EarlyView.
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang   +8 more
wiley   +1 more source

Is the brazilian diverse environment is a crib for the emergence and maintenance of exotic arboviruses?

open access: yesAnais da Academia Brasileira de Ciências
: We review the potential of Amazon forest as a source for circulation and maintenance of native arboviruses as well its capacity to host exotic arboviruses introduced in Brazil during their process of adapting to the Amazon environment.
DANIELE B.A. MEDEIROS   +1 more
doaj   +1 more source

The Nuclear Pore Complex: A Target for NS3 Protease of Dengue and Zika Viruses

open access: yesViruses, 2020
During flavivirus infection, some viral proteins move to the nucleus and cellular components are relocated from the nucleus to the cytoplasm. Thus, the integrity of the main regulator of the nuclear-cytoplasmic transport, the nuclear pore complex (NPC ...
Luis Adrián De Jesús-González   +11 more
doaj   +1 more source

Envelope Protein Ubiquitination Drives Zika Virus Entry and Pathogenesis

open access: yesNature, 2020
Zika virus (ZIKV) belongs to the family Flaviviridae, and is related to other viruses that cause human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurological disorders and replicates efficiently in reproductive tissues1–3 ...
M. Giraldo   +21 more
semanticscholar   +1 more source

Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity

open access: yesScience, 2017
One antibody for all and all antibodies for one Antibodies against related flavi-viruses such as dengue (DENV) and West Nile (WNV) can cross-react with Zika virus (ZIKV) and could thereby increase disease severity. Bardina et al.
Susana V. Bardina   +13 more
semanticscholar   +1 more source

Congenital Zika syndrome: A systematic review

open access: yesPLoS ONE, 2020
Background The signs and symptoms of Zika virus infection are usually mild and self-limited. However, the disease has been linked to neurological complications such as Guillain-Barré syndrome and peripheral nerve involvement, and also to abortion and ...
D. A. Freitas   +6 more
semanticscholar   +1 more source

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