Results 91 to 100 of about 121,530 (205)
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
Zika Virus Testing and Outcomes during Pregnancy, Florida, USA, 2016
Zika virus infection during pregnancy can lead to congenital Zika syndrome. Implementation of screening programs and interpretation of test results can be particularly challenging during ongoing local mosquitoborne transmission.
Colette Shiu +11 more
doaj +1 more source
Implicação do vírus Zika na causalidade da microcefalia : evidências atuais [PDF]
Apresenta dados atuais que comprovam a implicação do vírus Zika como agente causal da microcefalia. Com base nas evidências existentes até o momento, destaca-se a necessidade da continuidade de investimentos no SUS e em pesquisa, visando ao enfrentamento
Garcia, Leila Posenato
core
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du +9 more
wiley +1 more source
Yeni Bir Global Viral Etken: Zika virus
Zika virus ateşi bir flavirus'un neden olduğu sivrisineklerle bulaşan bir hastalıktır. Klinik tablo asemptomatik vakalardan ateş, başağrısı, yorgunluk, ve kutanöz döküntü ile ilişkili bir influanza benzeri sendroma kadar değişmektedir. Zika virus ilk kez
Gülfem Ece +2 more
doaj
Relato sobre o Zika vírus no Brasil [PDF]
Zika vírus, a Flavivirus first isolated in Africa, has spread to many countries around the world including Brazil. In this country, seven months after the football world cup, it was registered the occurrence of a epidemic, subsequently related to cases ...
Cipriano Monteiro, Carolina +1 more
core +1 more source
The Baboon as a Model to Study Human Health and Complex Disease
Baboons remain underappreciated as models of human biology and disease offering a distinct combination of biological and practical properties. In this review, we evaluate the baboon as a model for human complex diseases and make the case for broader use of baboons in translational research.
Brittany Hazzard, Yoav Gilad
wiley +1 more source
INTRODUÇÃO: No Brasil, a epidemia ocasionada pelo Zika Vírus gerou aumento de casos de microcefalia, caracterizando que mulheres infectadas durante o período gestacional transmitiram o vírus ao feto.
Monique Ornellas de Almeida Avelino +1 more
doaj +1 more source
The terpinolene + BMDB association caused severe midgut damage, increased apoptosis, reduced proliferation, and immune suppression in Ae. aegypti larvae, indicating that sublethal effects, despite higher LC50, compromise larval recovery and represent a promising strategy for integrated vector management.
Maria Clara da Nóbrega Ferreira Fernandes +9 more
wiley +1 more source
ABSTRACT Introduction Climate change has major health impacts to which researchers and policymakers need to respond. The volume and multidisciplinary nature of climate‐health evidence pose challenges to its comprehensive identification. Search filters are currently not available for this topic.
Maria‐Inti Metzendorf +6 more
wiley +1 more source

