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SUMMARYZika virus (ZIKV) is an arthropod-borne virus (arbovirus) in the genusFlavivirusand the familyFlaviviridae. ZIKV was first isolated from a nonhuman primate in 1947 and from mosquitoes in 1948 in Africa, and ZIKV infections in humans were sporadic for half a century before emerging in the Pacific and the Americas.
Lyle R, Petersen+2 more
+28 more sources
Identification of B-cell epitopes of Indian Zika virus strains using immunoinformatics [PDF]
IntroductionThe Zika virus is an emerging Flavivirus known to cause Zika infection in humans. It is associated with severe health problems such as microcephaly and Guillain-Barré syndrome post the Brazilian epidemic in 2015-16.
Rohan Raj Roy+5 more
doaj +2 more sources
Zika virus (ZIKV), a neurotropic single-stranded RNA flavivirus, remains an important cause of congenital infection, fetal microcephaly, and Guillain-Barré syndrome in populations where ZIKV has adapted to a nexus involving the Aedes mosquitoes and humans.
Sophie Masmejan+7 more
openaire +8 more sources
Background Zika virus is becoming one of the most widely transmitted arboviruses in the world. Development of antiviral inhibitor and vaccine requires an experimental system that allows rapid monitoring of the virus infection.
Jing Gao+6 more
doaj +1 more source
This commentary describes the creation of the Zika Virus Individual Participant Data Consortium, a global collaboration to address outstanding questions in Zika virus (ZIKV) epidemiology through conducting an individual participant data meta-analysis ...
Zika Virus Individual Participant Data Consortium
doaj +1 more source
Zika virus and Zika fever [PDF]
An emerging mosquito-borne arbovirus named Zika virus (ZIKV), of the family Flaviviridae and genus Flavivirus, is becoming a global health threat. ZIKV infection was long neglected due to its sporadic nature and mild symptoms. However, recently, with its rapid spread from Asia to the Americas, affecting more than 30 countries, accumulating evidences ...
Zhao-Yang Wang, Jing An, Peigang Wang
openaire +3 more sources
Zika virus and microcephaly [PDF]
Before 2015, Zika virus, a mosquito-transmitted flavivirus endemic to Africa and Southeast Asia, was thought to cause only a mild, self-limiting dengue-like illness. First discovered in 1947 in Uganda, the virus became epidemic in the Pacific islands 10 years ago.
Marina I. Salvadori, Michelle Barton
+11 more sources
Since its discovery in 1947 in Uganda, the Zika virus (ZIKV) remained in the shadows emerging in 2007 in Micronesia, where hundreds of dengue-like syndromes were reported. Then, in 2013-2014, it was rife in French Polynesia, where the first neurological effects were observed.
de Laval, Franck+5 more
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Calibration of a SEIR-SEI epidemic model to describe the Zika virus outbreak in Brazil [PDF]
Multiple instances of Zika virus epidemic have been reported around the world in the last two decades, turning the related illness into an international concern. In this context the use of mathematical models for epidemics is of great importance, since they are useful tools to study the underlying outbreak numbers and allow one to test the ...
arxiv +1 more source
The immunology of Zika Virus [PDF]
Zika virus (ZIKV) was initially thought to cause only mild, self-limiting symptoms. However, recent outbreaks have been associated with the autoimmune disease Guillain-Barré syndrome and causally linked to a congenital malformation known as microcephaly. This has led to an urgent need for a safe and effective vaccine.
Juthathip Mongkolsapaya+3 more
openaire +5 more sources