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Zika-virus-journal.pntd.0004702.PDF
, 2016 Zika virus infection during the third trimester of pregnancy may pose only minor risk for brain abnormalities in infants, according to a preliminary study published today in the New England Journal of Medicine. Health officials from Colombia and the U.S.
M,Javad.Aman (2853650)
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Zika Virus Impact, Diagnosis, Control, and Models, Volume 2: The Neuroscience of Zika Virus
, 2021 Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome.
core
Canadian Medical Association Journal, 2016 The symptoms of Zika virus infection may last up to one week and include a maculopapular rash, fever, joint and muscle pain, and conjunctivitis.[1][1],[2][2] Previous outbreaks in the Pacific Islands and the current outbreak have indicated a potential association with neurologic illnesses such ...
Derek R, MacFadden, Isaac I, Bogoch
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
International Journal of Infectious Diseases, 2017 Zika virus (ZIKV) is an emerging mosquito-borne virus that was first isolated from a sentinel rhesus monkey in the Zika Forest in Uganda in 1947. In Asia, the virus was isolated in Malaysia from Aedes aegypti mosquitoes in 1966, and the first human infections were reported in 1977 in Central Java, Indonesia.
Veasna Duong +2 more
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UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
Advanced Science, EarlyView.ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
Saudi Journal of Medicine and Medical Sciences, 2017 The Zika virus is an arbovirus belonging to the virus family Flaviviridae. The virus was isolated in 1947 from a rhesus monkey in the Zika Forest of Uganda. The virus causes sporadic mild human infections in Africa and later in Asia. However, by 2007 a major shift in its infection pattern was noticed and thousands of human infections were reported in ...
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Nature Reviews Microbiology, 2018 The recent epidemic of Zika virus (ZIKV) in the Americas has revealed the devastating consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome, characterized by malformations and microcephaly in neonates as well as developmental challenges in children, highlights the need for the development of a safe and effective ...
Peter Abbink +2 more
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