Results 121 to 130 of about 69,399 (238)
Immunodominant and highly conserved flavivirus envelope proteins can trigger cross-reactive IgG antibodies against related flaviviruses, which shapes subsequent protection or disease severity.
Tulika Singh +18 more
doaj +1 more source
Opportunities and Challenges for Surveillance of Congenital Anomalies in Sub‐Saharan Africa
ABSTRACT Introduction Congenital anomalies (CA) are ranked as the 3rd and 4th leading cause of neonatal and under‐5 mortality, respectively. Over 30% of infants born with a serious CA are found in sub‐Saharan Africa. Yet there are few robust epidemiological data on the burden and distribution of CA and associated mortality, disability, and morbidity ...
Emma Kalk +18 more
wiley +1 more source
Zika virus as an oncolytic treatment of human neuroblastoma cells requires CD24.
Neuroblastoma is the second most common childhood tumor. Survival is poor even with intensive therapy. In a search for therapies to neuroblastoma, we assessed the oncolytic potential of Zika virus. Zika virus is an emerging mosquito-borne pathogen unique
Joseph Mazar +7 more
doaj +1 more source
The impacts of biological invasions
ABSTRACT The Anthropocene is characterised by a continuous human‐mediated reshuffling of the distributions of species globally. Both intentional and unintentional introductions have resulted in numerous species being translocated beyond their native ranges, often leading to their establishment and subsequent spread – a process referred to as biological
Phillip J. Haubrock +42 more
wiley +1 more source
Zika virus infection and psychosis [PDF]
Joob, Beuy, Wiwanitkit, Viroj
openaire +4 more sources
Zika Virus Induces Apoptosis in Retinal Pigmented Epithelial Cells [PDF]
Zika virus is a single-stranded positive sense RNA virus that attracted international attention in 2015 when an epidemic broke out in Brazil. This vector borne virus is transmitted by mosquitos and is especially concerning for pregnant women because the ...
Kraus, Madison +2 more
core +1 more source
CRISPR‐Cas13a/Cas12a Assisted Dual Portable and Visualized HDV and HBV Detection
ABSTRACT Co‐infection with both hepatitis B virus (HBV) and hepatitis D virus (HDV) can aggravate the severity of the end‐stage liver disease and accelerate its progression. However, no combined diagnostic method for HDV and HBV nucleic acids exists. In this study, we have developed a highly sensitive and specific dual detection method for HDV RNA and ...
Yuan Tian +10 more
wiley +1 more source
Reverse Genetics of Orthoflaviviruses: Strategies for Constructing Functional or Infectious cDNA
ABSTRACT Reverse genetics (RG) systems have transformed RNA virus research by enabling the recovery of recombinant viruses entirely from cloned cDNA. These platforms allow precise, hypothesis‐driven manipulation of viral genomes and support systematic phenotypic analyses in vitro and in vivo.
Young‐Min Lee
wiley +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley +1 more source

