Results 71 to 80 of about 6,690 (224)

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

open access: yesAdvanced Science, Volume 12, Issue 43, November 20, 2025.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo   +7 more
wiley   +1 more source

Protective effects of long-term administration of Ziziphus jujuba fruit extract on cardiovascular responses in L-NAME hypertensive rats [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2018
Objective: Ziziphus jujuba stimulates the release of nitric oxide (NO).  Because NO is involved in cardiovascular regulations, in this study the effects of hydroalcoholic extract of Z.
Reza Mohebbati   +5 more
doaj   +1 more source

Modulatory Effects of Jujuboside A on Amino Acid Neurotransmitter Profiles in Tic Disorder

open access: yesBrain and Behavior, Volume 15, Issue 11, November 2025.
Jujuboside A ameliorates tic disorder in rats by reducing striatal glutamate and increasing GABA levels, with enhanced efficacy when combined with Tiapride, potentially through upregulation of glutamate transporters GLT‐1 and GLAST. ABSTRACT Objective This study investigates the impact of jujuboside A (JuA) on the levels of glutamate (Glu) and gamma ...
Fei Fan   +4 more
wiley   +1 more source

Polysaccharide from Ziziphus jujuba cv. Changzao prevented colitis in mice by regulating the inflammation-gut microbiota-metabolite axis

open access: yesJournal of Functional Foods
Polysaccharides derived from jujuba exhibit beneficial anti-ulcerative colitis effects, largely attributed to their potent antioxidant properties and other bioactivities.
Yina Huang   +8 more
doaj   +1 more source

Population Genetic Studies in Ziziphus jujuba Mill.: Multiple Molecular Markers (ISSR, SRAP, ITS, Cp-DNA)

open access: yesCaryologia, 2019
Ziziphus jujuba (jujube) is an important horticultural crop with medicinal value. It is under cultivation in many areas of Iran and also grows as wild in several geographical populations throughout the country.
Farah Farahani   +3 more
doaj   +1 more source

Medicine‐Food Plant Polysaccharides Modulate Diabetes and Diabetic Complications Through Maintaining Gut Function: A Review

open access: yesFood Frontiers, Volume 6, Issue 6, Page 2720-2765, November 2025.
Polysaccharides derived from medicine‐food plants restore intestinal barrier integrity and microbiota balance while modulating short‐chain fatty acid levels. These modifications significantly alleviate diabetes and its complications, including nephropathy, retinopathy, cardiovascular disease, and neuropathy.
Yi Long   +13 more
wiley   +1 more source

The complete genome of Ziziphus jujuba cv. dongzao, an economic crop in Yellow River Delta of China

open access: yesMitochondrial DNA. Part B. Resources, 2017
The complete chloroplast genome of Ziziphus jujuba cv. dongzao, known as an important economic cultivar in Yellow River Delta of China was reported. It exhibits a quadripartite structure with 161,493 bp including a large single copy region (89,178 bp), a
Chun-Ming Gao   +2 more
doaj   +1 more source

Anti-fertility effect of hydro-alcoholic extract of fennel (Foeniculum vulgare Mill) seed in male Wistar rats [PDF]

open access: yes, 2016
The study aimed to investigate the anti-fertility effect of fennel (Foeniculim vulgare Mill) seed extract in male rats. Material and Methods: Forty Wistar rats were divided into five equal groups.
Afrisham, Reza.   +7 more
core   +1 more source

Protective Effects of Exogenous Donkey Oil on Skin Healing Under Incisional Wound Damage

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 11, November 2025.
ABSTRACT Background The identification of cosmetic ingredients that promote wound healing with minimal inflammation is urgently needed. Donkey oil (DO) is a promising candidate due to its nutritional richness and biosafety. Aims This study aimed to evaluate the efficacy of DO in promoting wound healing and to elucidate its underlying mechanisms of ...
Jie Yu   +10 more
wiley   +1 more source

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