Results 211 to 220 of about 24,539,782 (228)

There Is no First Phase of the Jespersen Cycle1

Transactions of the Philological Society, EarlyView.
Abstract This paper challenges the traditional conception of the Jespersen Cycle by arguing that no ‘pure’ first phase of the cycle exists where a single negator operates without reinforcement. Drawing on historical data from Northern Italian dialects (Piedmontese, Lombard, Emilian), we demonstrate that emphatic negative structures systematically co ...
Tommaso Mattiuzzi, Cecilia Poletto
wiley   +1 more source

FK228-Mediated Restoration of Tight Junction Proteins in Diabetic Neuropathy. [PDF]

Biology (Basel)
Chen E, Thakur V, Chowdhury E, Misra A, Valdez C, Chattopadhyay M.   +5 more
europepmc   +1 more source

Is the rent too high? Land ownership and monopoly power

Real Estate Economics, EarlyView.
Abstract Pricing power in real estate markets can reduce housing supply and redevelopment relative to the social optimum. We show how pricing power interacts with popular redevelopment subsidies and zoning regulations. Using building‐level rental income data from NYC, we find that increased concentration is correlated with increased rents.
C. Luke Watson, Oren Ziv
wiley   +1 more source

Glucocorticoid-induced RPE injury in ARPE-19 cells: association with excessive autophagy and AMPK/mTOR signaling. [PDF]

Int J Ophthalmol
Guan WX, Guo Y, Chen ST, Liu ZM, Sun YY, Zhao MW.   +5 more
europepmc   +1 more source

Polypropylene Nanoplastic Exposure to Respiratory Epithelial Barrier‐On‐Chip and Interfacial Interactions With Human Serum Albumin

Allergy, EarlyView.
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert, Eyup Bilgi, Reyhan Coban, Pelin Saglam‐Metiner, Basar Dogan, Zeynep Imir‐Tekneci, Suleyman Selim Cinaroglu, Ozlem Goksel, Ceyda Oksel Karakus, Ozlem Yesil‐Celiktas   +9 more
wiley   +1 more source

Encephalomyocarditis virus impairs the blood-brain barrier by degrading tight junction proteins via AKT3-dependent autophagic and apoptotic pathways. [PDF]

Virulence
Dou X, Wang N, Yao S, Chen X, Li S, Xie J, Li X, Yang Y, Wen Y, Idris A, Li H, Feng R.   +11 more
europepmc   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Porcine iPSC-Derived Intestinal Cells as a High-Fidelity Platform for PEDV Pathogenesis. [PDF]

Animals (Basel)
Muangthong T, Chakritbudsabong W, Taowan J, Jantahiran P, Jaroensuk W, Kaeoket K, Rungarunlert S.   +6 more
europepmc   +1 more source

Deciphering the Potential Mechanism of Cordycepin in Alleviating Ulcerative Colitis via the AKT1 Signaling Pathway: An Integrated Approach Combining Network Pharmacology, Molecular Docking, and Experimental Validation. [PDF]

J Inflamm Res
Zhang W, Qian M, Jiang W, Chen J, Hu N, Jiang J.   +5 more
europepmc   +1 more source

Common Food Emulsifiers Impair Epithelial Barrier Integrity and Trigger Pro‐Inflammatory Responses and IgE Production

Allergy, EarlyView.
Soy lecithin and DATEM, the two commonly used food emulsifiers introduced into many foods including peanut butter and puffed bread, in the 2000s, impair intestinal epithelial barrier integrity in human gut‐on‐a‐chip and induced pluripotent stem cell colon organoid models.
Duygu Yazici, Yuka Hayashi, Yagiz Pat, Jennifer Hotie, Mehmet Ali Balci, Sena Ardicli, Juan Felipe Lopez, Ozge Ardicli, Bingjie Zhao, Angel Maldonado, Can Zeyneloglu, Kenji Matsumoto, Manru Li, Beate Rückhert, Lihong Chang, Ismail Ogulur, Vahap Eldem, Raja Dhir, Mubeccel Akdis, Kari Nadeau, Oscar Palomares, Hideaki Morita, Cezmi A. Akdis   +22 more
wiley   +1 more source