Results 1 to 10 of about 22,649 (238)

Comprehensive evaluation of compound Kushen injection combined with zoledronic acid in treating bone metastasis cancer pain based on meta-analysis and decision tree model [PDF]

open access: yesFrontiers in Pain Research
ObjectiveTo evaluate the safety, efficacy, and cost-effectiveness of combining Compound Kushen Injection (CKI) with zoledronic acid in the treatment of bone metastasis-induced cancer pain in malignant tumors.MethodsA comprehensive search of Chinese and ...
Xi Zhao   +5 more
doaj   +2 more sources

Delayed Inflammatory Reaction to Hyaluronic Acid Dermal Filler Following Zoledronic Acid Administration: A Case Report [PDF]

open access: yesClinical, Cosmetic and Investigational Dermatology
Nada J Alghamdi,1,* Serene R Almuhaidib,2,* Abdulmajeed S Alharbi,2,* Abdullah Ali N Aljalfan,1,* Khalid M Al-Husain1 1Department of Dermatology, King Fahd University Hospital, Al Khobar, Saudi Arabia; 2College of Medicine, Imam ...
Alghamdi NJ   +4 more
doaj   +2 more sources

How zoledronic acid improves osteoporosis by acting on osteoclasts

open access: yesFrontiers in Pharmacology, 2022
Osteoporosis is called a silent disease, because it is difficult to detect until comprehensive examinations for osteoporosis are performed or osteoporotic fractures occur.
Biao Wang   +4 more
doaj   +1 more source

Cost-Effectiveness of Sequential Denosumab/Zoledronic Acid Compared With Zoledronic Acid Monotherapy for Postmenopausal Osteoporotic Women in China

open access: yesFrontiers in Pharmacology, 2022
Objective: The primary purpose of this study was to estimate the cost-effectiveness of sequential denosumab/zoledronic acid versus zoledronic acid monotherapy for postmenopausal osteoporotic women in China.Methods: We updated and utilized a previously ...
Ruxu You   +8 more
doaj   +1 more source

Zoledronic acid induces ferroptosis by reducing ubiquinone and promoting HMOX1 expression in osteosarcoma cells

open access: yesFrontiers in Pharmacology, 2023
Aims: Ferroptosis plays important roles in tumorigenesis and cancer therapy. Zoledronic acid is known to inhibit the activity of farnesyl pyrophosphate synthase, a key enzyme in the mevalonate pathway.
Tianhao Ren   +10 more
doaj   +1 more source

Oral fibroblasts rescue osteogenic differentiation of mesenchymal stem cells after exposure to Zoledronic acid in a paracrine effect

open access: yesFrontiers in Pharmacology, 2023
Background: Medication-related osteonecrosis of the jaw is a serious complication that develops in oncologic patients treated with Zoledronic acid. Although used for over 30 years, the influence of Zoledronic acid on bone has been thoroughly investigated,
Tal Berg   +8 more
doaj   +1 more source

Cost-Effectiveness of Sequential Teriparatide/Zoledronic Acid Compared With Zoledronic Acid Monotherapy for Postmenopausal Osteoporotic Women in China

open access: yesFrontiers in Public Health, 2022
ObjectiveWe aimed to assess the cost-effectiveness of sequential teriparatide/zoledronic acid relative to zoledronic acid monotherapy for postmenopausal osteoporotic women in China.MethodsA previously validated Markov microsimulation model was updated to
Ruxu You   +7 more
doaj   +1 more source

Mesoporous bioactive glass/e-polycaprolactone scaffolds promote bone regeneration in osteoporotic sheep [PDF]

open access: yesActa Biomaterialia 90 (2019) 3693-402, 2021
Macroporous scaffolds made of a SiO2-CaO-P2O5 mesoporous bioactive glass (MBG) and epolycaprolactone (PCL) have been prepared by robocasting. These scaffolds showed an excellent in vitro biocompatibility in contact with osteoblast like cells (Saos 2) and osteoclasts derived from RAW 264.7 macrophages.
arxiv   +1 more source

Comparison of Denosumab and Zoledronic acid as neoadjuvant therapy in patients with giant cell tumor of bone

open access: yesJournal of Orthopaedic Surgery, 2021
Objectives: Both Zoledronic acid and denosumab have been utilized in neo-adjuvant setting for facilitating surgery and downsizing the lesion in Giant cell tumor (GCT).
Himanshu Kanwat   +5 more
doaj   +1 more source

Zoledronic acid as an adjuvant therapy in patients with breast cancer: a systematic review and meta-analysis. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Zoledronic acid is widely used as adjuvant chemotherapy for the treatment of breast cancer. However, previous trials reported inconsistent findings regarding their clinical efficacy and safety. We carried out a comprehensive systematic review
Wei-Wei Huang   +4 more
doaj   +1 more source

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