Reactive oxygen species and autophagy associated apoptosis and limitation of clonogenic survival induced by zoledronic acid in salivary adenoid cystic carcinoma cell line SACC-83. [PDF]
Salivary adenoid cystic carcinoma is an epithelial tumor in the head and neck region. Despite its slow growth, patients with salivary adenoid cystic carcinoma exhibit poor long term survival because of a high rate of distant metastasis. Lung and bone are
Xi-Yuan Ge+5 more
doaj +1 more source
Zoledronic acid-induced orbital inflammation [PDF]
A 62-year-old man was referred for left eye redness and pain from the emergency department. He had a medical history of metastatic castrate-sensitive prostate cancer, Gleason 9, with diffuse skeletal and pulmonary metastases diagnosed 1 year prior to presentation.
Muhammad Faran Khalid+3 more
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Zoledronic acid inhibits the bone metastasis of breast cancer by repressing exosome-loaded DKK1
This study is designed to investigate the mechanism underlying zoledronic acid for the bone metastasis of breast cancer. Dickkopf 1 (DKK1) was both expressed in breast cancer cells and exosomes isolated from breast cancer cells.
Bin Bin Song+4 more
doaj +1 more source
Annual Zoledronic Acid for the Treatment of Osteoporosis: A Randomized Controlled Trial
Context: Osteoporosis remains a significant public health problem in many parts of the world, including India. The efficacy of oral bisphosphonates is lower because of poor compliance.
Asif Hussain+5 more
doaj +1 more source
Zoledronic acid and ibandronic acid are listed in the Indonesian national formulary to prevent skeletal-related events (SRE) in patients diagnosed with bone metastasis in multiple myeloma (MM), with limited evidence to compare their effectiveness.
Nutrisia Aquariushinta Sayuti+3 more
doaj +1 more source
Ab initio investigation of the adsorption of zoledronic acid molecule on hydroxyapatite (001) surface: an atomistic insight of bone protection [PDF]
We report a computational study of the adsorption of zoledronic acid molecule on hydroxyapatite (001) surface within ab initio density functional theory. The systematic study has been performed, from hydroxyapatite bulk and surface, and zoledronic acid molecule to the adsorption of the molecule on the surface. The optimized bond lengths and bond angles
arxiv +1 more source
ObjectiveThis study aims to estimate the cost-effectiveness of yearly intravenous zoledronic acid treatment versus weekly oral alendronate for postmenopausal osteoporotic women in China.MethodsWe used a Markov microsimulation model to compare the cost ...
Ruxu You+8 more
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Zoledronic Acid Is Not Equally Potent on Osteoclasts Generated From Different Individuals
Zoledronic acid is a bisphosphonate commonly used to treat bone diseases such as osteoporosis and cancer‐induced bone disease. Patients exhibit a variable sensitivity to zoledronic acid; the underlying explanation for this remains unclear.
Anaïs M J Møller+5 more
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Zoledronic Acid–Induced Interface Dermatitis [PDF]
Zoledronic acid (ZA) is a bisphosphonate given intravenously, most commonly for the treatment of postmenopausal osteoporosis. Increase in usage of ZA because it was FDA-approved has resulted in increasing reports of side effects. For the most part, these are systemic.
Farah Succaria+2 more
openaire +2 more sources
Denosumab versus zoledronic acid in elderly patients after hip fracture
Background Two injectable anti-osteoporosis medications, denosumab and zoledronic acid, have been widely used to treat patients with severe osteoporosis.
Seung-Ju Kim, Ji Woon Kim, Dong-Woo Lee
doaj +1 more source