Results 11 to 20 of about 19,753 (208)
Adrenal Crisis Induced by Zoledronic Acid in Two Patients With Hypopituitarism: A Case Report and Literature Review. [PDF]
Case Rep EndocrinolAdrenal insufficiency (AI) is characterized by inadequate steroid hormone production and is frequently a consequence of hypopituitarism, which is also associated with increased risk of osteoporosis due to deficiencies in growth hormone, gonadotropins, and other pituitary hormones.
AlFaifi AM, AlMistehi WM.
europepmc +2 more sources
Effect of Zoledronic Acid on Skeletal Muscle After Bariatric Surgery: A Secondary Analysis From a Randomized Controlled Trial. [PDF]
Obesity (Silver Spring)ABSTRACT Objective This study aimed to investigate whether a single infusion of 5 mg zoledronic acid, given before bariatric surgery to prevent bone loss, could also hinder the loss of muscle mass, strength, and physical function. Methods In this double‐blinded study, patients referred for bariatric surgery were randomized 1:1 to either intervention ...
Gam S +4 more
europepmc +2 more sources
Zoledronic acid inhibits the bone metastasis of breast cancer by repressing exosome-loaded DKK1
Bangladesh Journal of Pharmacology, 2022 This study is designed to investigate the mechanism underlying zoledronic acid for the bone metastasis of breast cancer. Dickkopf 1 (DKK1) was both expressed in breast cancer cells and exosomes isolated from breast cancer cells.
Bin Bin Song +4 more
doaj +1 more source
Annual Zoledronic Acid for the Treatment of Osteoporosis: A Randomized Controlled Trial
Journal of Orthopedics, Traumatology and Rehabilitation, 2023 Context: Osteoporosis remains a significant public health problem in many parts of the world, including India. The efficacy of oral bisphosphonates is lower because of poor compliance.
Asif Hussain +5 more
doaj +1 more source
PLoS ONE, 2012 BackgroundZoledronic acid is widely used as adjuvant chemotherapy for the treatment of breast cancer. However, previous trials reported inconsistent findings regarding their clinical efficacy and safety.
Wei-Wei Huang +4 more
doaj +1 more source
Jurnal Manajemen dan Pelayanan Farmasi, 2020 Zoledronic acid and ibandronic acid are listed in the Indonesian national formulary to prevent skeletal-related events (SRE) in patients diagnosed with bone metastasis in multiple myeloma (MM), with limited evidence to compare their effectiveness.
Nutrisia Aquariushinta Sayuti +3 more
doaj +1 more source
Zoledronic Acid Is Not Equally Potent on Osteoclasts Generated From Different Individuals
JBMR Plus, 2020 Zoledronic acid is a bisphosphonate commonly used to treat bone diseases such as osteoporosis and cancer‐induced bone disease. Patients exhibit a variable sensitivity to zoledronic acid; the underlying explanation for this remains unclear.
Anaïs M J Møller +5 more
doaj +1 more source
Frontiers in Pharmacology, 2020 ObjectiveThis study aims to estimate the cost-effectiveness of yearly intravenous zoledronic acid treatment versus weekly oral alendronate for postmenopausal osteoporotic women in China.MethodsWe used a Markov microsimulation model to compare the cost ...
Ruxu You +8 more
doaj +1 more source
Denosumab versus zoledronic acid in elderly patients after hip fracture
Journal of Orthopaedic Surgery, 2022 Background Two injectable anti-osteoporosis medications, denosumab and zoledronic acid, have been widely used to treat patients with severe osteoporosis.
Seung-Ju Kim, Ji Woon Kim, Dong-Woo Lee
doaj +1 more source
Zoledronic acid inhibits the growth of leukemic MLL-AF9 transformed hematopoietic cells
Heliyon, 2020 A leukemic in vitro model produced by transducing Cord Blood derived-hematopoietic CD34+ cells with the MLL-AF9 translocation resulting in the oncogenic fusion protein, is used to assess for sensitivity to Zoledronic acid.
Emanuela Chiarella +9 more
doaj +1 more source