Results 81 to 90 of about 5,114,489 (264)

Zoledronic acid induced unilateral anterior uveitis

Indian Journal of Ophthalmology, 2020
Zoledronic acid is recommended for patients with osteoporosis. To report a case of unilateral anterior uveitis after zoledronate infusion. An osteoporotic patient presented with pain, visual loss, hyperemia, photophobia, and watering from the left eye ...
Shipra Gupta, Abhishek Onkar, Tushar Vashisht   +2 more
semanticscholar   +1 more source

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

Oral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem, Gavriel Chaushu, Daya Masri   +2 more
wiley   +1 more source

Local administration of zoledronic acid prevents traumatic osteonecrosis of the femoral head in rat model

Journal of Orthopaedic Translation, 2021
Background: Osteonecrosis of the femoral head (ONFH) is a refractory disease due to its unclear pathomechanism. Neither conservative treatment nor surgical treatment during the early stage of ONFH achieves satisfactory results. Therefore, this study aims
Jun Zhao, Tian Yue, Shibi Lu, Haoye Meng, Qiuxia Lin, Haiyang Ma, Guangbo Liu, Huo Li, Qiang Lu, Aiyuan Wang, Wenjing Xu, Jing Feng, Yiqun Wan, Sida Liao, Xuefeng Zhou, Jiang Peng   +15 more
doaj   +1 more source

Development, Evaluation, and Characterization of a Novel Mucoadhesive Film Containing Pterodon pubescens Benth Ethanolic Extract for Dental Use

Journal of Applied Polymer Science, Volume 142, Issue 45, December 5, 2025.
Pterodon pubescens Mucoadhesive Film for dental use. ABSTRACT Periodontal diseases involve infectious and inflammatory processes that affect oral tissues. Extracts from Pterodon pubescens Benth (sucupira) have demonstrated antinociceptive, anti‐inflammatory, anti‐edematogenic, and antiplatelet effects, highlighting their therapeutic potential for ...
Mariana Cecchetto Figueiredo, Fabiana Volpe Zanutto, Akmal Sabri, Tuany Zambroti Cândido, Leila Servat Medina, Ilza Maria de Oliveira Sousa, Rosanna Tarkany Basting, Lucia Elaine de Oliveira Braga, Ellen Cristina Souza de Oliveira, Simone Nataly Busato de Feiria, Bruno da Fonseca‐Santos, Marlus Chorilli, Ramiro Mendonça Murata, Mary Ann Foglio   +13 more
wiley   +1 more source

Antitumor Effects of Clinical Dosing Regimens of Bisphosphonates in Experimental Breast Cancer Bone Metastasis [PDF]

, 2017
Background Bisphosphonates exhibit direct antitumor activity in animal models, but only at high doses that are incompatible with the clinical dosing regimens approved for the treatment of cancer patients with skeletal metastases.
Clézardin, Philippe, Daubiné, Florence, Gasser, Juerg, Green, Jonathan, Le Gall, Céline   +4 more
core  

RTOG 0518: Randomized Phase III Trial to Evaluate Zoledronic Acid for Prevention of Osteoporosis and Associated Fractures in Prostate Cancer Patients [PDF]

, 2014
Background: RTOG 0518 evaluated the potential benefit of zoledronic acid therapy in preventing bone fractures for patients with high grade and/or locally advanced, non-metastatic prostate adenocarcinoma receiving luteinizing hormone-releasing hormone ...
Gore, Elizabeth, Kachnic, Lisa A., Kim, Harold E., Lawton, Colleen AF, Martin, Andre-Guy, Nabid, Abdenour, Pugh, Stephanie L, Shah, Amit B., Smith, Matthew, Tai, Patricia   +9 more
core   +1 more source

Guidelines for the Diagnosis and Treatment of Advanced Breast Cancer in China (2024 Edition)

Cancer Innovation, Volume 4, Issue 6, December 2025.
“The core objective of this guideline is to personalize the management of advanced breast cancer through molecular subtyping, optimizing the balance between survival and quality of life. We integrate recent evidence‐based advances and underscore the essential roles of multidisciplinary collaboration and management of patient‐reported outcomes (PROs ...
Breast Cancer Expert Committee of the National Quality Control Center for Cancer, Breast Cancer Expert Committee of the China Anti‐Cancer Association, Cancer Drug Clinical Research Committee of the China Anti‐Cancer Association   +2 more
wiley   +1 more source

Osteonecrosis of the jaw during biyearly treatment with zoledronic acid for aromatase inhibitor associated bone loss in early breast cancer: A literature review

Journal of Bone Oncology, 2015
Osteonecrosis of the jaw (ONJ) is one of the most relevant and specific complication of biphosphonates. ONJ in patients receiving zoledronic acid every 3 to 4 weeks is frequently described, but the ONJ biyearly regimen used to reduce aromatase inhibitor ...
Hampig Raphael Kourie, Joelle Antoun, Elie El Rassy, Marc Rassy, Claude Sader-Ghorra, Joseph Kattan   +5 more
doaj   +1 more source

Study of Adverse Effect Profile of Parenteral Zoledronic Acid in Female Patients with Osteoporosis [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Osteoporosis is still a under recognized entity in the population. Osteoporosis-related fractures can be prevented if people at risk can be screened, diagnosed and treated early.
Prem Kotian, Archith Boloor, Sushanth Sreenivasan   +2 more
doaj   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1463-1476, December 2025.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source