Results 51 to 60 of about 29,382 (227)

The development of contraceptive vaccines [PDF]

, 2002
The use of vaccination as a means of controlling fertility was established during the last decade with the publication of a successful Phase II trial demonstrating the efficacy of this approach to family planning.
Delves, PJ
core   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

A novel method for transmission electron microscopy study of cytoplasmic fragments from preimplantation human embryos [PDF]

, 2016
Transmission electron microscopy (TEM) is the main tool for exploring the intracellular damage and organelle distribution. The cause of producing embryo cytoplsamic fragmentation is not completely understood.
Halvaei, I, Khalili, Ma, Nottola, Stefania Annarita   +2 more
core   +1 more source

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

Advanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther, Tristin Schwartze, Jiying Zhang, Kun Fan, Gerard van der Zon, Luke Power, Cynthia S. Hinck, Claire Ciancia, Ananya Mukundan, Roman Gonzalez‐Prieto, Peter van Veelen, Rick M. Maizels, Andrew P. Hinck, Peter ten Dijke   +13 more
wiley   +1 more source

Freeze/thaw stress induces organelle remodeling and membrane recycling in cryopreserved human mature oocytes [PDF]

, 2016
Purpose: Our aim was to evaluate the ultrastructure of human metaphase II oocytes subjected to slow freezing and fixed after thawing at different intervals during post-thaw rehydration.
Albani, E., Borini, A., Coticchio, G., Levi Setti, P. E., Lorenzo, C., Macchiarelli, G., NOTTOLA, Stefania Annarita, Palmerini, M. G., Scaravelli, G.   +8 more
core   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

Animal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad, Hubdar Ali Kolachi, Jesse Oluwaseun Ayantoye, Xiaomeng Zhang, Muhammad Usman Mehmood, Rajilan Hilali Shanga, Pengcheng Wan, Xueming Zhao   +7 more
wiley   +1 more source

Protease activity involvement in the passage of mammalian sperm through the zona pellucida

Biological Research, 2011
The interaction between acrosome-reacted sperm and zona pellucida proteins is not yet fully understood. Serine protease acrosin and its zymogen proacrosin have been proposed to fulfill this function due to their capacity to bind zona pellucida ...
Ricardo D Moreno, Andrea Laserre A, Claudio Barros   +2 more
doaj  

Crossing the barrier or how regulation of ovastacin controls fertilization and translates into clinical phenotypes

iScience
Summary: The zona pellucida, a glycoprotein matrix enveloping the mammalian egg, exerts essential functions during fertilization and early embryonic development. Its safeguard property regulates sperm entry and thus indirectly controls fertility. Limited
Nele von Wiegen, Christian Behl, Hagen Körschgen   +2 more
doaj   +1 more source

Mechanical properties of zona pellucida hardening

European Biophysics Journal, 2009
We have investigated the changes in the mechanical properties of the zona pellucida (ZP), a multilayer glycoprotein coat that surrounds mammalian eggs, that occur after the maturation and fertilization process of the bovine oocyte by using atomic force spectroscopy.
Papi, Massimiliano, Brunelli, R., Sylla, L., Parasassi, T., Monaci, M., Maulucci, Giuseppe, Missori, M., Arcovito, G., Ursini, F., De Spirito, Marco   +9 more
openaire   +7 more sources

Zona pellucida antibodies in human sera [PDF]

Reproduction, 1982
Summary. A quantitative indirect immunofluorescent assay developed for the measurement of antibodies produced in rabbits against porcine zonae pellucidae was modified and used to detect autoantibodies specific to human zonae pellucidae.
P L, Nayudu, L E, Freemann, A O, Trounson   +2 more
openaire   +2 more sources