Anatomical landmarks and intraoperative "safe zone" for precise acetabular prosthesis placement in total hip arthroplasty for developmental dysplasia of the hip. [PDF]
Li B +5 more
europepmc +1 more source
A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang +15 more
wiley +1 more source
Initial Post-Commercialization Experience Using a Thoracic Branch Endoprosthesis: Broad Application to Real-World Patients. [PDF]
Lou X +9 more
europepmc +1 more source
Endothelial GPR68 is identified as a critical regulator of collateral artery growth in peripheral artery disease. Genetic and pharmacological evidence demonstrates that GPR68 integrates hemodynamic cues to drive monocyte recruitment and inflammatory remodeling, thereby promoting collateral arteriogenesis and tissue perfusion after ischemia ...
Yiyan Song +12 more
wiley +1 more source
Ets1-regulated endothelial-secreted factors promote compact myocardial growth and contribute to the pathogenesis of ventricular non-compaction. [PDF]
Wang L +7 more
europepmc +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
MRI-based classification of lateral hinge fractures in medial opening wedge high tibial osteotomy. [PDF]
Jung WH +4 more
europepmc +1 more source
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang +11 more
wiley +1 more source
Explant of an infected aortic arch fenestrated stent graft with extra-anatomic reconstruction. [PDF]
Koh EY, Tanaka A, Saqib NU, Estrera AL.
europepmc +1 more source
Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source

