Results 221 to 230 of about 29,405 (257)
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Insect cell‐derived human CD200‐Fc increases zonula occludens‐1 tight junction protein in urothelial carcinoma cells

Entomological Research, 2023
AbstractCD200 is a ligand that interacts with the CD200 receptor 1, with an anti‐inflammatory effect. CD200 inhibits the nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB) pathway, attenuating the inflammatory response and maintaining barrier function. In this study, human CD200 was fused with the fragment crystallizable (Fc) region
Da Won Lee   +9 more
openaire   +1 more source

Effect of hepatocyte growth factor on assembly of zonula occludens-1 protein at the plasma membrane

Journal of Cellular Physiology, 1998
Hepatocyte growth factor (HGF) is a paracrine cytokine that influences epithelial morphogenesis by modulating cell-cell adhesion and cell polarity. We have examined the role of HGF in the tight junction (TJ) formation. We followed the assembly and disassembly at the plasma membrane of the major component of the TJ, zonula occludens-1 (ZO-1) protein ...
GRISENDI S., ARPIN M., CREPALDI, Tiziana
openaire   +3 more sources

Increased interaction of connexin43 with zonula occludens-1 during inhibition of gap junctions by G protein-coupled receptor agonists

Cellular Signalling, 2012
Astrocytes are extensively coupled through gap junctions (GJs) that are composed of channels mostly constituted by connexin43 (Cx43). This astroglial gap junctional intercellular communication (GJIC) allows propagation of ions and signaling molecules critical for neuronal activity and survival.
Martine, Tencé   +3 more
openaire   +2 more sources

Nicotinamide dual treatment enhances morula-to-blastocyst transition through binding to Zonula Occludens-1 protein

Theriogenology
Nicotinamide (NAM) is a widely utilized compound in cell culture systems, yet its role during the morula-to-blastocyst transition remains underexplored. This study investigates the effects of NAM supplementation during both in vitro maturation (IVM) of oocytes and late-stage embryo culture (IVC3; the morula stage) on blastocyst development, metabolic ...
Marwa El-Sheikh   +6 more
openaire   +2 more sources

Effects of simulated weightlessness on tight junction protein occludin and Zonula Occluden-1 expression levels in the intestinal mucosa of rats

Journal of Huazhong University of Science and Technology [Medical Sciences], 2011
This study investigated the tight junction (TJ) protein expression of the intestinal mucosa in a rat tail-suspension model under simulated weightlessness. Twenty-four Wistar rats were randomly divided into three groups: CON group (n=8), control; SUS-14 d group (n=8), tail-suspension for 14 days; SUS-21 d group (n=8), tail-suspension for 21 days ...
Chen, Ying   +6 more
openaire   +2 more sources

Novel role of zonula occludens‐1: A tight junction protein closely associated with the odontoblast differentiation of human dental pulp cells

Cell Biology International, 2016
AbstractZonula occludens‐1 (ZO‐1), a tight junction protein, contributes to the maintenance of the polarity of odontoblasts and junctional complex formation in odontoblast layer during tooth development. However, expression and possible role of ZO‐1 in human dental pulp cells (hDPCs) during repair process remains unknown.
Jue, Xu   +6 more
openaire   +2 more sources

Interaction of Zonula Occludens-1 (ZO-1) with α-Actinin-4:  Application of Functional Proteomics for Identification of PDZ Domain-Associated Proteins

Journal of Proteome Research, 2006
The use of recombinant "bait" proteins to capture protein-binding partners, followed by identification of protein interaction networks by mass spectrometry (MS), has gained popularity and widespread acceptance. We have developed an approach using recombinant PDZ protein interaction modules of the membrane-associated guanylate kinase (MAGUK) protein ...
Vincent C, Chen   +3 more
openaire   +2 more sources

Research on the relationship between thick greasy tongue fur formation and vascular endothelial cell permeability with the protein expression of zonula occludens-1

Chinese Journal of Integrative Medicine, 2011
To determine the relationship of thick greasy tongue fur formation and permeability of vascular endothelial cells (ECs) with the protein expression of zonula occludens-1 (ZO-1).Sprague Dawley rats were randomly divided into a model group of severe acute pancreatitis (SAP) and a sham-operated (SO) group.
Wen-Jie, Qi   +5 more
openaire   +2 more sources

Tissue regression-related changes in connexin 43 and zonula occludens 1 gene and protein expression in the hen oviduct

Theriogenology
A growing body of evidence has highlighted the involvement of intercellular junctions in the remodeling of various tissues in physiological and pathological conditions. In this study, the hypothesis was that the expression of connexin 43 (Cx43 protein/GJA1 gene) and zonula occludens 1 (ZO1), crucial molecules of gap junctions and tight junctions ...
Karolina Frydrych   +3 more
openaire   +2 more sources

Flavivirus NS5 associates with host-cell proteins zonula occludens-1 (ZO-1) and regulating synaptic membrane exocytosis-2 (RIMS2) via an internal PDZ binding mechanism

bchm, 2009
Abstract Dengue virus (DENV) and tick-borne encephalitis virus (TBEV) are flaviviruses, which can cause lethal hemorrhagic fever and encephalitis, respectively. Here, we demonstrate that the TBEV-NS5 and DENV-NS5 proteins use an internal binding mechanism to target human PDZ proteins.
Karin, Ellencrona   +2 more
openaire   +2 more sources

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