Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Loss of Claudin‐18 (Cldn18) expression is a frequent and specific feature of non‐mucinous lung adenocarcinoma (NM‐LUAD). Cldn18 immunohistochemistry may serve as an ancillary tool for distinguishing malignant from non‐neoplastic alveolar epithelium, as well as for differentiating NM‐LUADs with mucin production from M‐LUADs, particularly in small or ...
Stefano Lucà +18 more
wiley +1 more source
PURPOSE. Hypoxia impairs the barrier function of the corneal epithelium. This function depends on tight junctions, of which zonula occludens (ZO)-1 is a major component.
Ji-Ae Ko +5 more
core
Unveiling cellular mechanisms underlying MYZAP related dilated cardiomyopathy using patient specific hiPSC cardiomyocytes. [PDF]
Zakzook F +8 more
europepmc +1 more source
Gut microbiota-mediated short-chain fatty acids contribute to the protective effects of Xiaoxuming decoction against lipopolysaccharide-induced acute lung injury. [PDF]
Yijin X +4 more
europepmc +1 more source
Zonula occludens toxin is a powerful mucosal adjuvant for intranasally delivered antigens
Zonula occludens toxin (Zot) is produced, by toxigenic strains of Vibrio cholerae and has the ability to reversibly alter intestinal epithelial tight junctions, allowing the passage of macromolecules through the mucosal barrier.
Marinaro M +4 more
core
Loss of Zonula Occludens-1 (ZO-1) Enhances Angiogenic Signaling in Ovarian Cancer Cells
Zonula occludens-1 (ZO-1), encoded by the TJP1 gene, is a crucial scaffolding protein within tight junctions that maintains epithelial and endothelial barrier integrity.
Heungyeol Kim +9 more
core +1 more source
High-salt diet promotes atopic dermatitis by partially enhancing intestinal SGK1/ENaC signaling and destroying gut <i>Lactobacillus</i>-maintained systemic type 1 interferon. [PDF]
Chen B, Yang J, Hao F, Song T.
europepmc +1 more source
Oxytocin supports the barrier integrity of brain endothelial cells via oxytocin receptors. [PDF]
Paolini C +4 more
europepmc +1 more source
Paeonol suppresses epithelial-mesenchymal transition-driven posterior capsular opacification through activation of AMPK signaling. [PDF]
Wang Q +8 more
europepmc +1 more source

