Results 11 to 20 of about 135,006 (287)
Factor XI antigen and activity in human platelets [PDF]
Blood, 1982 Abstract Washed platelets, contaminated with less than 0.20% plasma factor XI, were examined for the presence of factor XI antigen and activity. These platelets contained a factor-XI-like coagulant activity (0.67 +/- 0.11 U/10(11) platelets) that remained constant after successive washes.
Alvin H. Schmaier +4 more
openaire +4 more sources
Frontiers in Medicine, 2023 ObjectiveTransfusion of HLA-matched platelets can reduce the effect of alloimmune responses on platelet transfusion efficacy; however, finding HLA-matched platelets in the population is nearly impossible. Almost all HLA-matched platelets from related are
Jing-Cheng Zhang +3 more
doaj +1 more source
Human Platelet Antigen Genotyping and Expression of CD109 (Human Platelet Antigen 15) mRNA in Various Human Cell Types [PDF]
BioMed Research International, 2013 CD109 gene encodes a glycosylphosphatidylinositol-linked glycoprotein found in a subset of platelets and endothelial cell, and human platelet antigen (HPA) 15 is found on CD109. We evaluated the HPA genotype and/or the CD109 mRNA expression on two peripheral blood stem cells (PBSC), two peripheral bloods (PB), 12 granulocyte products, natural killer ...
Mi Jung Kim +12 more
openaire +3 more sources
Revista Brasileira de Hematologia e Hemoterapia, 2013 BACKGROUND: Immune platelet refractoriness is mainly caused by human leukocyte antigen antibodies (80-90% of cases) and, to a lesser extent, by human platelet antigen antibodies.
Carolina Bonet Bub +5 more
doaj +1 more source
Association of human platelet antigen polymorphisms with platelet count and mean platelet volume [PDF]
Hematology, 2018 Although recent genome-wide association studies have identified a number of single nucleotide polymorphisms associated with platelet count and mean platelet volume (MPV), it is unclear whether polymorphisms in the human platelet antigens (HPA) genes are associated with platelet count and MPV.
Ming Liu +5 more
openaire +2 more sources
Immunocytochemical Studies on Platelets. The Demonstration of a Common Antigen in Human Platelets and Megakaryocytes [PDF]
Blood, 1960 Abstract By means of the fluorescent antibody technic of Coons and Kaplan it was possible to demonstrate a common antigenic structure in human platelets and megakaryocytes, both in nonthrombocytopenic cases and in cases with idiopathic thrombocytopenic purpura.
Jacinto J. Vazquez, Jessica H. Lewis
openaire +3 more sources
Folia Histochemica et Cytobiologica, 2007 The pathogenesis and tissue damage that accompanies destruction of platelets in immune thrombocytopenias (IT) is still not understood very well and in addition to platelets, other cells (e.g.
Mariusz Z Ratajczak +5 more
doaj +1 more source
Rupture Forces among Human Blood Platelets at different Degrees of Activation [PDF]
, 2020 Little is known about mechanics underlying the interaction among platelets during activation and aggregation. Although the strength of a blood thrombus has likely major biological importance, no previous study has measured directly the adhesion forces of single platelet-platelet interaction at different activation states.
arxiv +1 more source
Neonatal Alloimmune Thrombocytopenia Detected After Traumatic Delivery: Case Report
Forbes Tıp Dergisi, 2021 Neonatal Alloimmune Thrombocytopenia (NAIT), a complication of maternal alloimmunization against fetal platelets, is the result of immune destruction of platelets due to maternal antibodies in the early period.
Gökhan Kaya, Sema Tanriverdi
doaj +1 more source
Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity [PDF]
, 2020 Antibodies recognizing complexes of the chemokine platelet factor 4 (PF4-CXCL4) and polyanions (P) opsonize PF4-coated bacteria hereby mediating bacterial host defense. A subset of these antibodies may activate platelets after binding to PF4-heparin complexes, causing the prothrombotic adverse drug reaction heparin-induced thrombocytopenia (HIT).
arxiv +1 more source