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Superoxide Dismutases in Pancreatic Cancer [PDF]
The incidence of pancreatic cancer is increasing as the population ages but treatment advancements continue to lag far behind. The majority of pancreatic cancer patients have a K-ras oncogene mutation causing a shift in the redox state of the cell ...
Justin G. Wilkes+2 more
doaj +3 more sources
Superoxide dismutase in leukocytes [PDF]
1 ] or NBT [ 141 in the xanthine-xanthine oxidase reaction. The reduction of NBT and cytochrome c was followed at 560 and 550 nm respectively. One unit of SOD activity is defined as the amount of enzyme that causes a decrease of the optical density from 0.025 to 0.0125 in 1 min using 1 cm light path cuvette.
Pierluigi Patriarca+2 more
openalex +5 more sources
Superoxide dismutase and neurological disorders
Superoxide dismutase (SOD) is a common antioxidant enzyme found majorly in living cells. The main physiological role of SOD is detoxification and maintain the redox balance, acts as a first line of defence against Reactive nitrogen species (RNS ...
Saravana Babu Chidambaram+7 more
doaj +3 more sources
Superoxide Dismutase Administration: A Review of Proposed Human Uses
Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant defense against oxidative stress in the body. SOD supplementation may therefore trigger the endogenous antioxidant machinery for the neutralization of free-radical ...
A. C. Rosa+4 more
semanticscholar +1 more source
Amide-π interactions in active centers of superoxide dismutase [PDF]
In this work, the influence of amide–π interactions on stability and properties of superoxide dismutase (SOD) active centres was analysed. In the data set of 43 proteins, 5017 amide–π interactions were observed, and every active centre formed averagely ...
Stojanović Srđan Đ.+2 more
doaj +1 more source
SUPEROKSIDA DISMUTASE (SOD) DAN RADIKAL BEBAS
Superoxide dismutase (SOD) is an endogenous antioxidant that works by regulating ROS levels. This group of enzymes functions to catalyze the efficient disposal of superoxide anions. Superoxide anions are produced enzymatically and non-enzymatically.
Evirosa Juliartha Simanjuntak+1 more
doaj +1 more source
BackgroundThis study aimed to estimate stress markers, oxidative stress (OS), reproductive hormones and sperm parameters in male smokers and non-smokers and observe the impact of oxidative stress markers and smoking on sperm count, motility and ...
Rehana Rehman+4 more
doaj +1 more source
Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury
Cisplatin is a chemotherapy agent commonly used to treat a wide variety of cancers. Despite the potential for both severe acute and chronic side effects, it remains a preferred therapeutic option for many malignancies due to its potent anti-tumor ...
Kranti A. Mapuskar+11 more
doaj +1 more source
The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6. The rate of autoxidation increases with increasing pH.
S. Marklund, Gudrun Marklund
semanticscholar +1 more source
Abstract Fresh chicken liver contains two types of superoxide dismutase, one of which is localized in the mitochondria while the other is found in the cytosol. The mitochondrial superoxide dismutase was inactivated by treatment with mixtures of chloroform and ethanol whereas the cytosol superoxide dismutase was not. The cytosol superoxide dismutase was
Richard A. Weisiger, Irwin Fridovich
openaire +2 more sources