Results 11 to 20 of about 10,158,137 (327)

Development of a Novel Evaluation Method for Endoscopic Ultrasound-Guided Fine-Needle Biopsy in Pancreatic Diseases Using Artificial Intelligence

Diagnostics, 2022
We aimed to develop a new artificial intelligence (AI)-based method for evaluating endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) specimens in pancreatic diseases using deep learning and contrastive learning.
Takuya Ishikawa, Masato Hayakawa, Hirotaka Suzuki, Eizaburo Ohno, Yasuyuki Mizutani, Tadashi Iida, Mitsuhiro Fujishiro, Hiroki Kawashima, Kazuhiro Hotta   +8 more
doaj   +2 more sources

Gut Dysbiosis in Pancreatic Diseases: A Causative Factor and a Novel Therapeutic Target

Frontiers in Nutrition, 2022
Pancreatic-related disorders such as pancreatitis, pancreatic cancer, and type 1 diabetes mellitus (T1DM) impose a substantial challenge to human health and wellbeing. Even though our understanding of the initiation and progression of pancreatic diseases
Tao Zhang, Tao Zhang, Tao Zhang, Guangqi Gao, Guangqi Gao, Guangqi Gao, Hafiz Arbab Sakandar, Hafiz Arbab Sakandar, Hafiz Arbab Sakandar, Lai-Yu Kwok, Lai-Yu Kwok, Lai-Yu Kwok, Zhihong Sun, Zhihong Sun, Zhihong Sun   +14 more
doaj   +2 more sources

The association between pancreatic diseases and pancreatic fat content: a cross-sectional study from the UK Biobank [PDF]

Frontiers in Endocrinology
ObjectiveMany researches have demonstrated an association between intra-pancreatic fat deposition (IPFD) and several pancreatic pathological conditions, including pancreatitis, pancreatic cancer, and type 2 diabetes mellitus (T2DM). The aim of this study
Jing Gao, Xiaowu Dong, Xiaolei Shi, Yuqing Yang, Weiwei Chen, Weiming Xiao, Guotao Lu, Xiaoping Yu   +7 more
doaj   +2 more sources

Nutritional Support in Pancreatic Diseases. [PDF]

Nutrients, 2022
This review summarizes the main pancreatic diseases from a nutritional approach. Nutrition is a cornerstone of pancreatic disease and is sometimes undervalued.
Cañamares-Orbís P, García-Rayado G, Alfaro-Almajano E.   +2 more
europepmc   +2 more sources

Understanding Necroptosis in Pancreatic Diseases. [PDF]

Biomolecules, 2022
Intermediate between apoptosis and necrosis, necroptosis is a regulated caspase-independent programmed cell death that induces an inflammatory response and mediates cancer development.
He R, Wang Z, Dong S, Chen Z, Zhou W.
europepmc   +2 more sources

Case Report: Partial response to single-agent pembrolizumab in a chemotherapy-resistant metastatic pancreatic cancer patient with a high tumor mutation burden

Frontiers in Oncology, 2023
Single-agent immune checkpoint blockade has shown no clinical benefits in pancreatic cancer. Recently, the programmed cell death protein 1 (PD-1) antibody pembrolizumab has been recommended as a treatment option for high tumor mutational burden (TMB ...
Mengyao Dai, Mengyao Dai, Mengyao Dai, Mengyao Dai, Jianpeng Sheng, Jianpeng Sheng, Jianpeng Sheng, Qi Zhang, Qi Zhang, Qi Zhang, Qi Zhang, Jianxin Wang, Jianxin Wang, Jianxin Wang, Jianxin Wang, Qihan Fu, Qihan Fu, Qihan Fu, Qihan Fu, Tingbo Liang, Tingbo Liang, Tingbo Liang, Tingbo Liang   +22 more
doaj   +1 more source

Positive feedback between lncRNA FLVCR1-AS1 and KLF10 may inhibit pancreatic cancer progression via the PTEN/AKT pathway

Journal of Experimental & Clinical Cancer Research, 2021
Background FLVCR1-AS1 is a key regulator of cancer progression. However, the biological functions and underlying molecular mechanisms of pancreatic cancer (PC) remain unknown.
Jiewei Lin, Shuyu Zhai, Siyi Zou, Zhiwei Xu, Jun Zhang, Lingxi Jiang, Xiaxing Deng, Hao Chen, Chenghong Peng, Jiaqiang Zhang, Baiyong Shen   +10 more
doaj   +1 more source

A case of walled‐off necrosis extending into the pelvic cavity successfully treated by endoscopic necrosectomy using a lumen‐apposing metal stent

DEN Open, 2022
A 31‐year‐old man developed massive walled‐off necrosis extending into the pelvic cavity following severe acute alcoholic pancreatitis. Endoscopic ultrasound‐guided fistula drainage was performed using a lumen‐apposing metal stent, but this was ...
Makoto Morita, Tomoyuki Yokota, Ryo Yano, Michiko Amano, Hironori Ochi, Nobuaki Azemoto, Toshie Mashiba, Kouji Joko   +7 more
doaj   +1 more source

LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma

Journal of Hematology & Oncology, 2022
Background LncRNA-PACERR plays critical role in the polarization of tissue-associated macrophages (TAMs). In this study, we found the function and molecular mechanism of PACERR in TAMs to regulate pancreatic ductal adenocarcinoma (PDAC) progression ...
Yihao Liu, Minmin Shi, Xingfeng He, Yizhi Cao, Pengyi Liu, Fanlu Li, Siyi Zou, Chenlei Wen, Qian Zhan, Zhiwei Xu, Jiancheng Wang, Baofa Sun, Baiyong Shen   +12 more
doaj   +1 more source

Pro-Inflammatory Food, Gut Microbiota, and Cardiovascular and Pancreatic Diseases. [PDF]

Biomolecules
Recent studies have shown that a pro-inflammatory diet and dysbiosis, especially a high level of trimethylamine-N-oxide (TMAO), are associated with various adverse health conditions.
Chen B, Patel S, Bao L, Nadeem D, Krittanawong C.   +4 more
europepmc   +2 more sources