Results 21 to 30 of about 6,319,763 (285)
Nature Communications, 2020 Metastasis can occur following surgical resection of solid tumors and metastasis is the main cause of cancer death. The role of anesthetics used during surgery in cancer metastasis and the underlying mechanism remains largely unknown.
Ru Li, Yujie Huang, Jun Lin
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The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain [PDF]
Korean Journal of Anesthesiology, 2014 BackgroundGeneral anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia.
Ji-Hyun Lee +6 more
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General Anesthetics Activate a Potent Central Pain-Suppression Circuit in the Amygdala
Nature Neuroscience, 2020 General anesthesia (GA) can produce analgesia (loss of pain) independent of inducing loss of consciousness, but the underlying mechanisms remain unclear. We hypothesized that GA suppresses pain in part by activating supraspinal analgesic circuits.
Thuy Hua +10 more
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General Anesthetics on Immune System Cytokines: A Narrative Review Article
Anesthesiology and Pain Medicine, 2020 Context According to the previous studies, general anesthesia influences the immune system. Evaluating such impacts on the immune system helps to improve the management of anesthesia.
A. Jafarzadeh +4 more
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BMC Anesthesiology, 2021 Background Although general anesthetics depress spontaneous respiration, the comprehensive effect of general anesthetics on respiratory function remains unclear. We aimed to investigate the effects of general anesthetics on spontaneous respiration in non-
Xuechao Hao +3 more
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Volatile Anesthetics Regulate Anti-Cancer Relevant Signaling
Frontiers in Oncology, 2021 Volatile anesthetics are widely used inhalation anesthetics in clinical anesthesia. In recent years, the regulation of anti-cancer relevant signaling of volatile anesthetics has drawn the attention of investigators.
Jiaqiang Wang +5 more
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Frontiers in Neurology, 2022 General anesthetics-induced neurotoxicity and cognitive impairment in developing brains have become one of the current research hotspots in the medical science community.
Jiaojiao Wang, Jiaojiao Wang, Zhihui Liu
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Frontiers in Synaptic Neuroscience, 2022 General anesthetics disrupt brain processes involved in consciousness by altering synaptic patterns of excitation and inhibition. In the cerebral cortex and hippocampus, GABAergic inhibition is largely mediated by inhibitory interneurons, a heterogeneous
Iris A. Speigel +2 more
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A Double-Edged Sword: Volatile Anesthetic Effects on the Neonatal Brain
Brain Sciences, 2014 The use of volatile anesthetics, a group of general anesthetics, is an exceedingly common practice. These anesthetics may have neuroprotective effects. Over the last decade, anesthetic induced neurotoxicity in pediatric populations has gained a certain ...
Sunny Chiao, Zhiyi Zuo
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Journal of Anesthesia, 2019 General anesthetics are commonly used in major surgery. To achieve the depth of anesthesia for surgery, patients are being subjected to a variety of general anesthetics, alone or in combination.
Lingzhi Wu, Hailin Zhao, H. Weng, D. Ma
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