Results 21 to 30 of about 47,583 (239)
Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population [PDF]
, 2012 Background: The ‘exposome’ represents the accumulation of all environmental exposures across a lifetime. Topdown strategies are required to assess something this comprehensive, and could transform our understanding of how environmental factors affect ...
Athersuch, Toby J. +10 more
core +4 more sources
BioTechniques, 2016 The free nucleoside 2′-deoxyguanosine (dGuo) is the most susceptible to oxidation by reactive oxygen species (ROS) compared to the other free nucleosides, and its oxidation product 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo) has been used as a ...
Patrícia S. Peres +2 more
doaj +1 more source
Acta Veterinaria, 2021 The aim of this study was to determine the effects of L-carnitine and magnesium on the levels of tissue malondialdehyde, 8-hydroxy-2’-deoxyguanosine, and cytokines (tumor necrosis factor alpha, interleukin-6) in streptozotocin-induced experimental ...
Senturk Meryem +2 more
doaj +1 more source
Environmental conditions can modulate the links among oxidative stress, age, and longevity [PDF]
, 2017 Understanding the links between environmental conditions and longevity remains a major focus in biological research. We examined within-individual changes between early- and mid-adulthood in the circulating levels of four oxidative stress markers linked ...
Boner, Winnie +5 more
core +1 more source
The role of some oxidative stress and inflammatory factors in essential hypertension [PDF]
Zanco Journal of Medical Sciences, 2018 Background and Objective: Oxidative stress and inflammation are cooperative events involved in essential hypertension development. This study aimed to evaluate the association of N-terminal pro-Brain natriuretic peptide, matrix-metalloprotinase-9 and 8 ...
Julian Yonan Ismaeil +1 more
doaj +1 more source
Crystal structure of the nucleoside 2′-deoxyguanosine dimethyl sulfoxide disolvate
Acta Crystallographica Section E: Crystallographic Communications, 2023 The title compound, C10H13N5O4·2C2H6OS, which is of interest with respect to its biological activity, at 183 K has orthorhombic (P212121) crystal symmetry. The structure displays a network of intermolecular N—H...N, N—H...O and O—H...O hydrogen bonds. 2′-
Bernhard Spingler
doaj +1 more source
Nickel(II)-catalysed oxidative guanine and DNA damage beyond 8-oxoguanine [PDF]
, 2007 Oxidative DNA damage is one of the most important and most studied mechanisms of disease. It has been associated with a range of terminal diseases such as cancer, heart disease, hepatitis, and HIV, as well as with a variety of everyday ailments.
Kelly, Michele C. +3 more
core +1 more source
Interaction of low-energy electrons with the purine bases, nucleosides, and nucleotides of DNA [PDF]
, 2006 The authors report results from computational studies of the interaction of low-energy electrons with the purine bases of DNA, adenine and guanine, as well as with the associated nucleosides, deoxyadenosine and deoxyguanosine, and the nucleotide ...
McKoy, Vincent, Winstead, Carl
core +1 more source
Biotinylation of Deoxyguanosine at the Abasic Site in Double-Stranded Oligodeoxynucleotides
Journal of Analytical Methods in Chemistry, 2016 Biotinylation of deoxyguanosine at an abasic site in double-stranded oligodeoxynucleotides was studied. The biotinylation of deoxyguanosine is achieved by copper-catalyzed click reaction after the conjugation of the oligodeoxynucleotide with 2-oxohex-5 ...
Chun Wu
doaj +1 more source
Anchor-based bisulfite sequencing determines genome-wide DNA methylation
Communications Biology, 2022 Anchor-Based Bisulfite Sequencing (ABBS) is a sequencing based method that enables analysis of DNA methylation states, based on specific hybridization of bisulfite-refractory methylcytosines with 8-aza-7-deaza-2-deoxyguanosine, incorporated in a primer ...
Nathaniel Chapin +3 more
doaj +1 more source