Results 21 to 30 of about 59,785 (337)
Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences [PDF]
Leonora Balaj+2 more
exaly +2 more sources
Neutrophil microvesicles and their role in disease [PDF]
Microvesicles are formed through shedding from the plasma membrane, a process shared by almost all human cells. Microvesicles are highly abundant and have been detected in blood, urine, cerebrospinal fluid, and saliva. They contain a library of cargo derived from their parental cell during formation, including proteases, micro-RNAs and lipids and ...
Reece Dow, Victoria Ridger
openaire +3 more sources
Microvesicles Transfer Mitochondria and Increase Mitochondrial Function in Brain Endothelial Cells
We have demonstrated, for the first time that microvesicles, a sub-type of extracellular vesicles (EVs) derived from hCMEC/D3: a human brain endothelial cell (BEC) line transfer polarized mitochondria to recipient BECs in culture and to neurons in mice ...
A. D'Souza+15 more
semanticscholar +1 more source
R(h)oads to microvesicles [PDF]
A novel form of cell-to-cell communication involving the formation and shedding of large vesicular structures, called microvesicles (MVs), from the surfaces of highly aggressive forms of human cancer cells has been attracting increasing amounts of attention. This is in large part due to the fact that MVs contain a variety of cargo that is not typically
Marc A. Antonyak+2 more
openalex +3 more sources
Decoding the microvesicle message [PDF]
Isobel Barry
openalex +2 more sources
The Immunomodulatory Role of Syncytiotrophoblast Microvesicles
Immune adaptation is a critical component of successful pregnancy. Of primary importance is the modification of cytokine production upon immune activation. With the discovery that normal pregnancy itself is a pro-inflammatory state, it was recognised that the classical Th1/Th2 cytokine paradigm, with a shift towards 'type 2' cytokine production ...
Jennifer H. Southcombe+3 more
openalex +8 more sources
Microvesicles and Viral Infection [PDF]
ABSTRACTCells secrete various membrane-enclosed microvesicles from their cell surface (shedding microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly, these vesicles have many characteristics in common with enveloped viruses, including biophysical properties, biogenesis, and uptake by cells. Recent discoveries describing
Nancy Raab-Traub, David G. Meckes
openaire +3 more sources
Circulating Microvesicles Are Elevated Acutely following Major Burns Injury and Associated with Clinical Severity. [PDF]
Microvesicles are cell-derived signaling particles emerging as important mediators and biomarkers of systemic inflammation, but their production in severe burn injury patients has not been described.
Kieran P O'Dea+6 more
doaj +1 more source
Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots [PDF]
This study describes a simple technique that improves a recently developed 3D sub-diffraction imaging method based on three-photon absorption of commercially available quantum dots.
A Franceschetti+28 more
core +12 more sources
Microvesicles as immune orchestra conductors
In this issue of Blood, Sprague and colleagues report that platelet-derived membrane vesicles (PDMVs) orchestrate an immune response sufficient to deliver CD154 signals, which stimulate antigen-specific IgG production and modulate germinal-center formation, by cooperating with responses elucidated by CD4+ T cells.
Mariusz Z. Ratajczak
openalex +5 more sources