Results 21 to 30 of about 10,158,137 (327)

Ameliorative Effects of Gut Microbial Metabolite Urolithin A on Pancreatic Diseases

Nutrients, 2022
Urolithin A (Uro A) is a dietary metabolite of the intestinal microbiota following the ingestion of plant-based food ingredients ellagitannins and ellagic acid in mammals.
Kailin Li, Yao Xiao, Jinxin Bian, Lin Han, Caian He, E. El-Omar, L. Gong, Min Wang   +7 more
semanticscholar   +1 more source

Application of exosomes in the diagnosis and treatment of pancreatic diseases

Stem cell research & therapeutics, 2022
Pancreatic diseases, a serious threat to human health, have garnered considerable research interest, as they are associated with a high mortality rate.
Li Han, Z. Zhao, Ke Yang, Mei Xin, Lichen Zhou, Siping Chen, Shibo Zhou, Zheng Tang, Hua Ji, Ruiwu Dai   +9 more
semanticscholar   +1 more source

Microbiota in Pancreatic Diseases: A Review of the Literature

Journal of Clinical Medicine, 2021
The gut microbiota is a critical element in the balance between human health and disease. Its impairment, defined as dysbiosis, is associated with gastroenterological and systemic diseases.
T. Schepis, S. S. De Lucia, E. Nista, Vittoria Manilla, G. Pignataro, V. Ojetti, A. Piccioni, A. Gasbarrini, F. Franceschi, M. Candelli   +9 more
semanticscholar   +1 more source

Real‐world implications of nonbiological factors with staging, clinical management, and prognostic prediction in pancreatic ductal adenocarcinoma

Cancer Medicine, 2023
Background The American Joint Committee on Cancer (AJCC) tumor‐node‐metastasis (TNM) staging system focuses on traditional biological factors (BFs). The present study incorporates nonbiological factors (NBFs) into the AJCC‐TNM staging system in terms of ...
Chao Wang, Haoda Chen, Xiaxing Deng, Wei Xu, Baiyong Shen   +4 more
doaj   +1 more source

Distinguishing diabetes secondary to pancreatic diseases from type 2 diabetes mellitus

Current Opinion in Gastroenterology, 2021
Purpose of review Diabetes secondary to pancreatic diseases (i.e., acute pancreatitis, chronic pancreatitis, and pancreatic cancer) is increasingly studied, but remains challenging to distinguish from type 2 diabetes (T2DM).
P. Hart, D. Andersen, M. Petrov, M. Goodarzi   +3 more
semanticscholar   +1 more source

Development and validation of a cancer stem cell-related signature for prognostic prediction in pancreatic ductal adenocarcinoma

Journal of Translational Medicine, 2020
Background Cancer stem cells (CSCs) are crucial to the malignant behaviour and poor prognosis of pancreatic ductal adenocarcinoma (PDAC). In recent years, CSC biology has been widely studied, but practical prognostic signatures based on CSC-related genes
Zengyu Feng, Minmin Shi, Kexian Li, Yang Ma, Lingxi Jiang, Hao Chen, Chenghong Peng   +6 more
doaj   +1 more source

Sildenafil Enhances the Therapeutic Effect of Islet Transplantation for Diabetic Peripheral Neuropathy via mTOR/S6K1 Pathway

International Journal of Endocrinology, 2023
Purpose. This study aimed to investigate the potential mechanism underlying the therapeutic effect of sildenafil in combination with islet transplantation for diabetic peripheral neuropathy. Methods.
Xiandong Zhu, Shangjing Xie, Jiawei Chen, Qiaohong Lu, Xiaowu Wang, Feixiang Duan, Sinian Xu, Yan Zhang, Hongjian Huang, Yongqiang Wang, Hongwei Wang, Bicheng Chen, Huanjie Huang   +12 more
doaj   +1 more source

Establishment of a 3D culture model in vitro of pancreatic cancer primary cells using hydrogel microspheres

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Objective·To establish an in vitro culture model mimicking tumor microenvironment using hydrogel microspheres and fresh primary pancreatic cancer cells.Methods·The morphological distribution of the hydrogel microspheres was recorded, observed and ...
MA Fangfang, QIN Jiejie, REN Lingjie, TANG Xiaomei, LIU Jia, SHI Minmin, JIANG Lingxi   +6 more
doaj   +1 more source

RETRACTED ARTICLE: The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA

Journal of Hematology & Oncology, 2022
Background Although a substantial increase in the survival of patients with other cancers has been observed in recent decades, pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest diseases. No effective screening approach exists.
Zengyu Feng, Kexian Li, Kai Qin, Juyong Liang, Minmin Shi, Yang Ma, Shiwei Zhao, Huaiyu Liang, Dongni Han, Baiyong Shen, Chenghong Peng, Hao Chen, Lingxi Jiang   +12 more
doaj   +1 more source

The Role of Endocrine Disruption Chemical-Regulated Aryl Hydrocarbon Receptor Activity in the Pathogenesis of Pancreatic Diseases and Cancer. [PDF]

Int J Mol Sci
The aryl hydrocarbon receptor (AHR) serves as a ligand-activated transcription factor crucial for regulating fundamental cellular and molecular processes, such as xenobiotic metabolism, immune responses, and cancer development.
Kim K.
europepmc   +2 more sources