The International Journal of Artificial Organs, 1996 Uremic pruritus and its treatment are reviewed. Pruritus affects 50-90% of patients undergoing peritoneal dialysis or hemodialysis; symptoms usually begin about six months after the start of dialysis and range from localized and mild to generalized and severe.
K, Hiroshige, A, Kuroiwa
openaire +4 more sources
A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. [PDF]
, 2019 Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies.
Apostol, George +15 more
core +2 more sources
The Neuromodulatory Effect of Antipruritic Treatment of Chronic Prurigo
Dermatology and Therapy, 2019 Chronic prurigo is an extremely severe pruritic skin disease which presents with multiple, hyperkeratotic and erosive papules, nodules and/or plaques.
Claudia Zeidler +2 more
doaj +1 more source
Emerging Methods to Objectively Assess Pruritus in Atopic Dermatitis. [PDF]
, 2019 INTRODUCTION:Atopic dermatitis (AD) is an inflammatory skin disease with a chronic, relapsing course. Clinical features of AD vary by age, duration, and severity but can include papules, vesicles, erythema, exudate, xerosis, scaling, and lichenification.
Bhutani, Tina +7 more
core +1 more source
Pathological Skin Picking: Case Presentation and Review of the Literature [PDF]
, 2015 Pathological skin picking is a condition in which patients induce skin lesions through repetitive, compulsive excoriations of normal skin or skin with minor surface irregularities and they admit their role in the production of the lesions, but are unable
Benea, Vasile +5 more
core +6 more sources
Pruritus in Autoimmune and Inflammatory Dermatoses
Frontiers in Immunology, 2019 Pruritus in autoimmune and inflammatory dermatoses is a common symptom that can be severe and affect the quality of life of patients. In some diseases, pruritus is related to disorders activity and severity or may occur independent of the disease ...
Claudia Zeidler +7 more
doaj +1 more source
Proteomic and phosphoproteomic analysis reveals that neurokinin-1 receptor (NK1R) blockade with aprepitant in human keratinocytes activates a distinct subdomain of EGFR signaling: Implications for the anti-pruritic activity of NK1R antagonists [PDF]
, 2019 Background: Epidermal growth factor receptor (EGFR) inhibitors can cause serious cutaneous toxicities, including pruritus and papulopustular acneiform skin eruptions.
Boozalis, Emily +10 more
core +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Itch in Scabies—What Do We Know?
Frontiers in Medicine, 2021 Scabies is a common parasitic skin infestation characterized by severe itch and a heterogenous clinical presentation. Itch, as the cardinal symptom of scabies, is imposing a high burden on affected patients and is often difficult to manage.
Sascha Ständer, Sonja Ständer
doaj +1 more source
Pruritus is a common feature in sheep infected with the BSE agent. [PDF]
, 2008 BACKGROUND: The variability in the clinical or pathological presentation of transmissible spongiform encephalopathies (TSEs) in sheep, such as scrapie and bovine spongiform encephalopathy (BSE), has been attributed to prion protein genotype, strain ...
Bellworthy, SJ +11 more
core +3 more sources