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3-Methyl-1-(prop-2-en-1-yl)quinoxalin-2(1H)-one
In the molecule of the title compound, C12H12N2O, the quinoxaline ring is planar with an r.m.s. deviation of 0.007 (15) Å. The dihedral angle between the quinoxaline and propenyl planes is 82.1 (2)°.
Youssef Ramli+4 more
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Quinoxalines are a group of antibiotics widely used in medicine to fight bacterial infections.These antibiotics have a broad spectrum of action and belong to the class of 4 quinolones. Theirmechanism of action is based on inhibiting the activity of bacterial enzymes responsible for DNAsynthesis, which leads to their death. Due to this, quinoxalines are
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Quinoxaline Derivatives as Antiviral Agents: A Systematic Review
Background: In recent decades, several viruses have jumped from animals to humans, triggering sizable outbreaks. The current unprecedent outbreak SARS-COV-2 is prompting a search for new cost-effective therapies to combat this deadly pathogen.
Marc Montana+3 more
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A series of novel V-shaped quinoxaline, [1,2,5]oxadiazolo[3,4-b]pyrazine and [1,2,5]thiadiazolo[3,4-b]pyrazine push–pull derivatives with 2,4′-biphenylene linker were designed and their electrochemical, photophysical and nonlinear optical properties were
Egor V. Verbitskiy+7 more
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Diazanaphthalenes: A 13C NMR investigation on the site of protonation and pKa values [PDF]
The pH dependence of the 13C chemical shifts (δ) of the diazanaphthalenes has been recorded. From this dependence the pKa values have been determined using the Henderson-Hasselbach equation.
Meer, Douwe van der+2 more
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Quinoxaline, its derivatives and applications: a state of the art review [PDF]
Quinoxaline derivatives are an important class of heterocycle compounds, where N replaces some carbon atoms in the ring of naphthalene. Its molecular formula is C8H6N2, formed by the fusion of two aromatic rings, benzene and pyrazine.
Cordeiro, M. Natália D. S.+6 more
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Quinoxaline is a heterocyclic compound with a two-membered ring structure that undergoes redox cycling to produce toxic free radicals. It has antiviral, antibacterial, antifungal, and antitumor activities.
Abdallah Alhaj Sulaiman+5 more
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Medicinal chemistry is a basic science that involves identification, synthesis and development of new drugs for therapeutic use. Biological importance of heterocycles makes them more crucial in pharmaceutical industries.In this work heterocyclics like ...
Geethavani Meka, Ramakrishna Chintakunta
doaj
A new Z' = 1 crystal structure of quinoxaline (or 1,4-diaza-naphthalene), C(8)H(6)N(2), with one-fifth the volume of the earlier known Z' = 5 structure was obtained by means of an in situ cryocrystallization technique.
Ranganathan, Sathishkumar+3 more
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the very different redox behaviour of isoelectronic complexes with [PtCl2] and [AuCl2]+ [PDF]
The new, potentially ambidentate heterocyclic ligand 2,3-bis(1-methylimidazol-2-yl)quinoxaline (bmiq) was obtained from 2,3-bis(1-methylimidazol-2-yl)glyoxal and 1,2-diaminobenzene.
Bulak, Ece+6 more
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