Results 181 to 190 of about 11,054,575 (256)
Intrahippocampally Injected Human Recombinant Clusterin Reduces Amyloid-β Aggregate Size in Cerebral Arteriole Walls of Clusterin Knockout Mice. [PDF]
Laslo A+11 more
europepmc +1 more source
FAILURE TO OBSERVE TOLERANCE TO THE HYPERALGESIC EFFECT OF NALOXONE IN MICE
K. Ramabadran
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Towards a National Longitudinal Tracking Framework of Health Graduate Practice Locations. [PDF]
Versace VL+4 more
europepmc +1 more source
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Factors Contributing to Geographical Variation in Maternal Smoking Rates Among Aboriginal and Torres Strait Islander Women. [PDF]
Cameron E+7 more
europepmc +1 more source
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
An Intervention to Build Grit, Resilience and a Growth Mindset in Physiotherapy Students. [PDF]
Calo M+6 more
europepmc +1 more source