Results 81 to 90 of about 1,026 (107)

In Vivo Synaptic Density Imaging with 11C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease. [PDF]

open access: yesJ Nucl Med, 2019
Toyonaga T   +11 more
europepmc   +1 more source

A new phenylstannyl precursor for synthesizing [11C]UCB-J

open access: yesA new phenylstannyl precursor for synthesizing [11C]UCB-J
openaire   +1 more source

Building an open infrastructure for molecular neuroimaging: Standards and tools from the OpenNeuroPET initiative. [PDF]

open access: yesJ Cereb Blood Flow Metab
Ganz M   +19 more
europepmc   +1 more source

Effects of radiotherapy on synaptic density as assessed by [11C]UCB-J PET in the brains of patients with head and neck cancer

open access: yes
van der Weijden, Chris W.J.   +7 more
openaire   +1 more source

Principal component analysis of synaptic density measured with [11C]UCB-J PET in Alzheimer's disease

The American Journal of Geriatric Psychiatry, 2021
Introduction Synaptic loss has been cited as an early pathological event and major structural correlate of cognitive impairment in Alzheimer's disease (AD). However, this observation is based on limited neuropathological studies. Here, we examined the in vivo relationship between synaptic density and cognitive performance in early AD using [11C]UCB-J ...
Ryan O'Dell   +17 more
openaire   +1 more source

Synaptic density is associated with cognitive performance in Alzheimer’s disease: A PET imaging study with [11C]UCB‐J

Alzheimer's & Dementia, 2021
AbstractBackgroundFor 30 years synapse loss has been referred to as the major pathological correlate of cognitive impairment in Alzheimer’s disease (AD). However, this statement is based on remarkably few patients studied by autopsy or biopsy in limited brain regions, largely at the moderate to severe stages of disease.
Christopher H. van Dyck   +16 more
openaire   +1 more source

Synaptic density is associated with cognitive performance in early Alzheimer's disease: a PET imaging study with [11C]UCB-J

The American Journal of Geriatric Psychiatry, 2021
Introduction For 30 years synapse loss has been referred to as the major pathological correlate of cognitive impairment in Alzheimer's disease (AD; Terry, et al. 1991; DeKosky and Scheff. 1990). However, this statement is based on remarkably few patients studied by autopsy or biopsy in limited brain regions, largely at the moderate to severe stages of
Emily Sharp   +16 more
openaire   +1 more source

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