Results 81 to 90 of about 1,026 (107)
In Vivo Synaptic Density Imaging with 11C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease. [PDF]
Toyonaga T +11 more
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A new phenylstannyl precursor for synthesizing [11C]UCB-J
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Mapping the Synaptome in Neurodegeneration: Emerging Clinical Applications of SV2A PET Imaging. [PDF]
Filippi L, Nuvoli S, Spanu A, Palumbo B.
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Building an open infrastructure for molecular neuroimaging: Standards and tools from the OpenNeuroPET initiative. [PDF]
Ganz M +19 more
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Principal component analysis of synaptic density measured with [11C]UCB-J PET in Alzheimer's disease
The American Journal of Geriatric Psychiatry, 2021Introduction Synaptic loss has been cited as an early pathological event and major structural correlate of cognitive impairment in Alzheimer's disease (AD). However, this observation is based on limited neuropathological studies. Here, we examined the in vivo relationship between synaptic density and cognitive performance in early AD using [11C]UCB-J ...
Ryan O'Dell +17 more
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Alzheimer's & Dementia, 2021
AbstractBackgroundFor 30 years synapse loss has been referred to as the major pathological correlate of cognitive impairment in Alzheimer’s disease (AD). However, this statement is based on remarkably few patients studied by autopsy or biopsy in limited brain regions, largely at the moderate to severe stages of disease.
Christopher H. van Dyck +16 more
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AbstractBackgroundFor 30 years synapse loss has been referred to as the major pathological correlate of cognitive impairment in Alzheimer’s disease (AD). However, this statement is based on remarkably few patients studied by autopsy or biopsy in limited brain regions, largely at the moderate to severe stages of disease.
Christopher H. van Dyck +16 more
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The American Journal of Geriatric Psychiatry, 2021
Introduction For 30 years synapse loss has been referred to as the major pathological correlate of cognitive impairment in Alzheimer's disease (AD; Terry, et al. 1991; DeKosky and Scheff. 1990). However, this statement is based on remarkably few patients studied by autopsy or biopsy in limited brain regions, largely at the moderate to severe stages of
Emily Sharp +16 more
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Introduction For 30 years synapse loss has been referred to as the major pathological correlate of cognitive impairment in Alzheimer's disease (AD; Terry, et al. 1991; DeKosky and Scheff. 1990). However, this statement is based on remarkably few patients studied by autopsy or biopsy in limited brain regions, largely at the moderate to severe stages of
Emily Sharp +16 more
openaire +1 more source

