Results 141 to 150 of about 88,586 (196)

Investigating the impact of residual refraction within ±1.0 dioptre on uncorrected distance visual acuity in pseudophakic eyes: a cross-sectional study. [PDF]

BMJ Open
Li D, Zhang J, Jin L, Han X, Chen L, Liu Y, Cai W, Cao Q.   +7 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

ATM Inhibition Enhances Knock-in Efficiency by Suppressing AAV-Induced Activation of Apoptotic Pathways. [PDF]

Commun Biol
Natsagdorj ME, Hara H, Uosaki H, Nakahara F, Inoue M, Hanazono Y.   +5 more
europepmc   +1 more source

Cation–Anion Synergy Enables Uniform and Stable SAMs for High‐Efficiency Perovskite/TOPCon Tandem Solar Cells

Advanced Science, EarlyView.
A cation‐anion synergistic strategy is developed to enhance self‐assembled monolayer (SAM) adsorption using guanidinium thiocyanate (GuaSCN). Guanidinium (Gua⁺) suppresses micelle aggregation, while thiocyanate (SCN−) promotes phosphonic acid deprotonation and strengthens ionic bonding to the substrate.
Haofan Ma, Xin Li, Huan Li, Jianmin Guan, Luyao Zheng, Jun Wu, Ziyu He, Yunyun Yu, Jungan Wang, Jie Yang, Xinyu Zhang, Meili Zhang, Yuheng Zeng, Menglei Xu, Zhiqin Ying, Xi Yang, Jichun Ye   +16 more
wiley   +1 more source

Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury

Advanced Science, EarlyView.
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie, Gulimire Yilihan, Qiong Chen, Dachuan Lin, Zhen Liu, Mengyi Yuan, Yujia Wang, Haoteng Xu, Weishang Zhou, Wanxin Gong, Yueer Li, Chen Peng, Tong Yang, Peng Gao, Qing Liu, Xin‐Hua Feng, Mu Xiao, Chao Jiang   +17 more
wiley   +1 more source

Engineered biodegradable polymeric nanoparticles injectable system of atorvastatin for improved therapeutic activity. [PDF]

Sci Rep
Venkatraman R, B Narayanan VH, Nowakowski S, Nellinger S, Kluger P, Kopka B, Brzezinski M, Sankar A, Durai R.   +8 more
europepmc   +1 more source

Water‐Soluble Metal Phthalocyanines Enable Molecularly Dispersed Heterogeneous Electrochemical CO2 Conversion

Advanced Science, EarlyView.
Water‐soluble metallophthalocyanines self‐assemble onto the surface of carbon black via π–π interactions, creating highly dispersed and electronically coupled MPcTs/CB, which enables selective CO2‐to‐CO conversion in aqueous media with near‐quantitative Faradaic efficiency and remarkable stability. Optimized flow‐cell operation delivers up to 500 mA cm−
Xiangyu Zhang, Shoulong Pan, Yu Li, Pan Li, Zizi Ruan, Qing Bai, Qinglin Jiang, Cheng Zhou, Bing Yang, Liang Yao, Yuguang Ma   +10 more
wiley   +1 more source

Comparative spectral analysis of blood and saliva in breast cancer, benign breast disease and healthy controls using ATR-FTIR. [PDF]

Sci Rep
de Andrade Marques L, Silva ATF, Ferreira ICC, Santos LLD, Pereira JCP, Santos DW, Paiva CE, de Paiva Maia YC.   +7 more
europepmc   +1 more source

Designing Scalable Mechano‐Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral Inactivation

Advanced Science, EarlyView.
Can a surface be designed to physically break viruses? This study explores how nanoscale geometry—specifically the spacing of tiny pillars—can determine whether viruses remain intact or rupture. Using flexible acrylic and a scalable fabrication process, the authors develop nanopillared, transparent surfaces that show strong antiviral activity without ...
Samson W. L. Mah, Denver P. Linklater, Vassil Tzanov, Chaitali Dekiwadia, Sergey Rubanov, Phuc H. Le, Laleh Tafakori, Ranya Simons, Graeme Moad, Soichiro Saita, Takashi Yanagishita, Hideki Masuda, Vladimir Baulin, Natalie A. Borg, Elena P. Ivanova   +14 more
wiley   +1 more source