Results 81 to 90 of about 278 (209)

Patient‐Centric First‐in‐Human Dose Selection: An Ex Vivo Minimal Anticipated Biological Effect Level Approach for T‐Cell Engagers in Multiple Myeloma

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The minimal anticipated biological effect level (MABEL) approach to first‐in‐human (FIH) dose calculation can lead to long dose‐escalation periods before observing clinical activity. We used a novel ex vivo MABEL approach to calculate the FIH starting dose for forimtamig, a T‐cell bispecific antibody under investigation for the treatment of relapsed ...
Thomas E. Kraft   +16 more
wiley   +1 more source

High-order functional redundancy in ageing explained via alterations in the connectome in a whole-brain model. [PDF]

open access: yesPLoS Comput Biol, 2022
Gatica M   +7 more
europepmc   +1 more source

Sustainability‐Oriented Collaborations in Green Energy Markets Formation: A Configurational Analysis of Alliance Management Capabilities and Relational View

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Sustainability‐oriented collaborations are inter‐organisational arrangements where the competencies of multiple companies are pooled together to tackle environmental challenges. These collaborations differ from traditional strategic alliances in that they tackle complex goals amidst greater uncertainties that extend beyond economic performance,
Vittorio Maria Garibbo   +3 more
wiley   +1 more source

Geometric Model and Calibration Method for a Solid-State LiDAR. [PDF]

open access: yesSensors (Basel), 2020
García-Gómez P   +3 more
europepmc   +1 more source

Impact of QSW‐ZVS on Input EMI Filter Design in DC‐DC Converters

open access: yesInternational Journal of Circuit Theory and Applications, EarlyView.
This paper analyzes the impact of quasi‐square wave zero voltage switching (QSW‐ZVS) on passive EMI filter design for DC‐DC buck converters. The extra element theorem (EET) is used to derive the design quantities that ensure converter performance is not altered, and the resulting damping element values are compared with those of traditional converters.
Silvia Simone   +3 more
wiley   +1 more source

Aggregating distributed energy resources for grid flexibility services: A distributed game theoretic approach

open access: yesInternational Journal of Robust and Nonlinear Control, EarlyView., 2023
Abstract We propose a hierarchical energy management scheme for aggregating Distributed Energy Resources (DERs) for grid flexibility services. To prevent a direct participation of numerous prosumers in the wholesale electricity market, aggregators, as self‐interest agents in our scheme, incentivize prosumers to provide flexibility. We firstly model the
Xiupeng Chen   +3 more
wiley   +1 more source

A DNA damage multiscale model for NTCP in proton and hadron therapy. [PDF]

open access: yesMed Phys, 2020
Abolfath R   +4 more
europepmc   +1 more source

Photometric Diagnostic of the Sheath Dynamics and Electron Density Trends in Single and Dual Frequency CCRF Argon Plasmas

open access: yesContributions to Plasma Physics, EarlyView.
ABSTRACT A methodological study is presented on a noninvasive photometric diagnostic for determining trends in electron density and sheath dynamics in single (1f) and a dual (2f) radio frequency capacitively coupled (CCRF) argon plasmas. The 1f discharges are operated at 13.56 and 27.12 MHz, respectively, while the 2f discharge is driven by both ...
Daniel Zuhayra   +3 more
wiley   +1 more source

Evolutionary dynamics on a regular networked structured and unstructured multi‐population

open access: yesInternational Journal of Robust and Nonlinear Control, EarlyView., 2023
Abstract In this paper, we study collective decision‐making in a multi‐population framework, where groups of individuals represent whole populations that interact by means of a regular network. Each group consists of a number of players and every player can choose between two options.
Wouter Baar   +2 more
wiley   +1 more source

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