Proteomic and Transcriptomic Signatures of Poor Asthma Symptom Control in the U‐BIOPRED Cohort
No stable features were identified as associated with asthma symptom control in transcriptomics or sputum proteomics. Higher TWEAKR/TNFRSF12A and MBL/MBP‐C serum levels increased the odds of uncontrolled symptoms, while higher MK08/MAPK8 and CD5L serum levels decreased the odds, after adjustment for clinical variables.
Joana Antão +294 more
wiley +1 more source
Increasing Filamins A and B in Th2 Lymphocytes as a Therapeutic Opportunity to Attenuate Airway Inflammation in Mice. [PDF]
Chamy L +7 more
europepmc +1 more source
Rapid Human Skin Barrier Disruption by Sodium Dodecyl Sulfate and Associated Molecular Mechanisms
Short‐term exposure to SDS rapidly disrupts human skin barrier integrity within minutes, as detected by real‐time electrical impedance spectroscopy. SDS‐induced barrier dysfunction is driven by oxidative stress, leading to suppression of immune/barrier mediators and activation of stress, lipid remodeling, and epidermal differentiation pathways ...
Manru Li +10 more
wiley +1 more source
Scientific integrity from a meta-ethical perspective: more contextualization and research ethics committees? A preliminary meta-ethics study. [PDF]
Stoeklé HC, Lasterie R, Hervé C.
europepmc +1 more source
From Loss to Transformation? Towards Pluralistic and Politicised Agrarian‐Climate Futures
ABSTRACT Understanding how actors perceive and anticipate future states of the world is gaining traction in climate change governance scholarship and related calls for sustainability transformations. However, smallholder farmers, indigenous groups, and local communities, who are expected to bear disproportionate burdens of loss and damage from climate ...
Joel Persson +4 more
wiley +1 more source
Editorial: The role of empathy in behavioral change toward ethical consumption and environmental sustainability. [PDF]
Gaspar A +3 more
europepmc +1 more source
Liquid Assemblies: An Institutional Design for Liquid Democracy
Constellations, EarlyView.
Chiara Valsangiacomo Balmelli +1 more
wiley +1 more source
ABSTRACT Responsible leadership can be manifested in a variety of ways but we lack understanding of what drives this variation and what the implications are of different approaches. In this conceptual article, we develop a novel typology of responsible leadership approaches based on leaders' different perceived obligations as experts, facilitators, and
Christian Voegtlin, Andrew Crane
wiley +1 more source
Occupational class and dementia mortality: evidence from Belgian census-linked data. [PDF]
Dinneweth J, Van den Borre L, Gadeyne S.
europepmc +1 more source
ABSTRACT Artificial intelligence (AI)‐generated synthetic data has emerged as a promising solution to address the underrepresentation of underserved populations in medical AI systems. By artificially generating data that mimics real‐world patient information, proponents argue that AI‐generated synthetic data can fill data gaps, improve algorithmic ...
Stéphanie Baggio
wiley +1 more source

