Results 131 to 140 of about 4,466,005 (254)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

MODES D'EVALUATION (PROCESSUS/CONTENU) ET PERFORMANCE DES PROJETS DE R&D. LES RESULTATS D'UNE RECHERCHE EMPIRIQUE [PDF]

A partir des résultats d'une recherche empirique, la communication examine les différents modes d'évaluation de performance des projets de R&D. Nos résultats montrent qu'il est plus pertinent d'évaluer les dimensions de la performance des projets de R&D ...
Papa Ibra Kebe
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Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Évaluation des troubles de la personnalité et MMPI-2 : questions, échelles et stratégies

European Psychiatry, 2000
openaire   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Quelle évaluation des enseignants au service de l'école? actes du Séminaire 2007, Leysin, 6 et 7 décembre 2007 / [PDF]

Titre de l'écran-titre (visionné le 16 juin 2008 ...
Séminaire Quelle évaluation des enseignants au service de l'école (2007 : Leysin, Suisse), Weiss, Jacques   +1 more
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Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Évaluation des troubles de la personnalité

European Psychiatry, 2000
openaire   +1 more source

Strategic equity compensation: A delphi-AHP approach to industry-specific governance design for RSUs. [PDF]

PLoS One
Park WA, Sernova E, Park CY.
europepmc   +1 more source

Developing a knowledge base in Conservation Agriculture in Lao PDR 2008-2009 [PDF]

, 2010
Chabanne, André, Chantharath, Bounsay, Jullien, Frédéric, Lienhard, Pascal, Panyasiri, Khamkèo, Rattanatray, Bounmy, Tivet, Florent, Tran Quoc Hoa,   +7 more
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